Question · asked by 1 review
Oral misoprostol 20 µg hourly titrated vs oral misoprostol 25 µg two‐hourly static: Vaginal birth within 24 hours
- Population
- induction of labour.
- Intervention
- Oral misoprostol 20 µg hourly titrated
- Comparison
- oral misoprostol 25 µg two‐hourly static
- Outcome
- Vaginal birth within 24 hours
Oral misoprostol 20 µg hourly titrated showed no clear difference in vaginal birth within 24 hours compared with oral misoprostol 25 µg two‐hourly static (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Oral misoprostol 20 µg hourly titrated vs oral misoprostol 25 µg two‐hourly static Vaginal birth within 24 hours · induction of labour. Oral misoprostol 20 µg hourly titrated showed no clear difference in vaginal birth within 24 hours compared with oral misoprostol 25 µg two‐hourly static (low certainty). Low‐dose oral misoprostol for induction of labour (2021) · Cochrane Headline outcomes only | RR 0.97 [0.8, 1.16] | 2 studies · 296 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Low‐dose oral misoprostol for induction of labour 2021 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.