Findings

What do systematic reviews say?

4,411 questions · 5,986 findings · 226 reviews · Oral Health

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No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Partial caries removal (single stage; residual dentinal caries sealed into the tooth definitively) vs Complete caries removal

Signs or symptoms of pulpal disease · Patients with carious teeth, affecting any tooth surface(s), in unrestored primary and permanent teeth

Partial caries removal (single stage; residual dentinal caries… showed no clear difference in signs or symptoms of pulpal disease compared with complete caries removal (low certainty).

1 finding from 1 review

Operative caries management in adults and children 2013 · Cochrane All outcomes
1 year
RR 0.27 [0.05, 1.60]
3 studies · 172 participants
Low

Acupuncture vs sham

Dry mouth (xerostomia) · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome

Acupuncture showed no clear difference in dry mouth (mouth dryness, different scales) compared with placebo (sham acupuncture) (low certainty).

1 finding from 1 review

Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
End of treatment (4-6 weeks)
SMD -0.34 [-0.81, 0.14]
2 studies · 70 participants
Low

Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) vs paracetamol

Patients not using rescue medication at 6 hours · Patients with pain after surgical removal of lower wisdom teeth (third molars) requiring bone removal or with baseline moderate to severe…

Ibuprofen (single postoperative oral dose; 200 mg to 512 mg) leads to higher patients not using rescue medication at 6 hours compared with paracetamol (acetaminophen) (single postoperative oral dose; 600 mg… (high certainty).

1 finding from 1 review

Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth 2013 · Cochrane All outcomes
6 hours postdosing · Ibuprofen 400 mg vs paracetamol 1000 mg
RR 1.50 [1.25, 1.79]
4 studies · 542 participants
High

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Patients' quality of life · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Intraoral distalising appliance vs Another (different) intraoral distalising appliance

Non-compliance rate of the intervention · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…

The review found no eligible studies for this question.

1 finding from 1 review

Orthodontic treatment for distalising upper first molars in children and adolescents 2013 · Cochrane All outcomes
Non-compliance rate not reported ("The remaining secondary outcomes and adverse effects were not reported by these studies").
0 studies
No studies found

Toluidine blue (visual staining) vs No screening

Outcome not reported · Planned population: general population or high-risk / opportunistic screening groups (no eligible study)

The review found no eligible studies for this question.

1 finding from 1 review

Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes
There was no evidence to support the use of adjunctive technologies like toluidine blue, brush biopsy or fluorescence imaging as a screening tool to reduce oral cancer mortality; no eligible randomised controlled trial…
0 studies
No studies found

Immediate loading vs Conventional loading

Implant failure · Patients who are having osseointegrated root-form dental implants

Immediate loading showed no clear difference in implant failure compared with conventional loading; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: different times for loading dental implants 2013 · Cochrane All outcomes
1 year
RR 1.50 [0.60, 3.77]
10 studies
GRADE not reported

Powered toothbrush (any mode of action) vs Manual toothbrush

Unstimulated whole saliva (UWS) · Adults with medication-related dry mouth

Powered toothbrush showed no clear difference in unstimulated whole saliva (UWS) compared with manual toothbrush; GRADE not reported.

1 finding from 1 review

Interventions for the management of dry mouth: non‐pharmacological interventions 2013 · Cochrane All outcomes
45 minutes after brushing
MD -0.07 [-0.74, 0.60]
1 study
GRADE not reported

Resin composite restorations containing antibacterial agents vs Non-antibacterial containing composite restorations

Postoperative sensitivity, marginal adaptation, anatomic form and other clinical outcomes (USPHS restoration quality; includes tooth vitality and pulpitis) · Adults and adolescents in any age group with restorations in the permanent dentition and children with restorations in the primary dentition

The review found no eligible studies for this question.

1 finding from 1 review

Antibacterial agents in composite restorations for the prevention of dental caries 2013 · Cochrane All outcomes
No studies were included in this review, as we were unable to find any trials directly comparing antibacterial containing composites to other active interventions or controls.
0 studies
No studies found

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Postoperative infection · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in postoperative infection compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications 2013 · Cochrane All outcomes
3 to 5 months
RR 0.69 [0.36, 1.35]
6 studies · 1162 participants
GRADE not reported

Two miniplates (transbuccal approach) vs One miniplate plus two screws (intraoral approach at external oblique ridge)

Restoration of function (malocclusion) · Adults with fractures of the mandibular angle

Two miniplates (transbuccal approach) showed no clear difference in restoration of function (malocclusion) compared with one miniplate plus two screws (intraoral approach at external…; GRADE not reported.

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
Angle of mandible only
RR 0.46 [0.05, 4.17]
1 study
GRADE not reported

Primary school-based behavioural intervention (both oral hygiene and dietary components) vs No treatment (or delayed treatment)

Caries increment, tooth index D(M)FT · Children aged 4 to 12 years attending primary school

1 finding from 1 review

Primary school‐based behavioural interventions for preventing caries 2013 · Cochrane All outcomes
2 years
PF 0.49
1 study
GRADE not reported

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Patients' quality of life · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

Intraoral distalising appliance vs Headgear (extraoral appliance)

Movement of upper incisor teeth (mm) · Children and adolescents (aged 16 years or less at the start of treatment) undergoing orthodontic treatment to distalise upper first…

Intraoral distalising appliance may leads to higher movement of upper incisor teeth (mm) compared with headgear (extraoral appliance) (low certainty).

1 finding from 1 review

Orthodontic treatment for distalising upper first molars in children and adolescents 2013 · Cochrane All outcomes
MD 1.82 [1.39, 2.24]
4 studies · 150 participants
Low

Zygomatic implants without bone grafts (as a complete alternative to any bone augmentation procedure) vs Conventional dental implants in augmented maxillae

Implant failure rate · Participants with an atrophic maxilla who cannot be rehabilitated with conventional dental implants due to lack of bone (including…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for replacing missing teeth: dental implants in zygomatic bone for the rehabilitation of the severely… 2013 · Cochrane All outcomes
At least 1 year in function
Results (Effects of interventions): we could not identify any eligible randomised controlled trials (RCTs).
0 studies
No studies found

Primary school-based behavioural intervention (both oral hygiene and dietary components) vs No treatment (or delayed treatment)

Frequency of cariogenic food and drink consumption · Children aged 4 to 12 years attending primary school

1 finding from 1 review

Primary school‐based behavioural interventions for preventing caries 2013 · Cochrane All outcomes
Worthington 2001: few children had problems identifying foods containing sugar; only 15% of intervention and 19% of control participants reported routinely consuming sugary snacks on arriving home from school; snacking…
1 study
GRADE not reported

Self etching primer (one-step etchant-and-primer technique) vs Conventional etchants (two-step etch and prime method using 37% phosphoric acid)

Participant satisfaction · Children and adults with fixed orthodontic brackets bonded to incisors, canines and premolars

The review found no eligible studies for this question.

1 finding from 1 review

Enamel etching for bonding fixed orthodontic braces 2013 · Cochrane All outcomes
Participant satisfaction: No studies assessed this outcome.
Studies not reported
No studies found

Brush biopsy (oral cytology) vs No screening

Outcome not reported · Planned population: general population or high-risk / opportunistic screening groups (no eligible study)

The review found no eligible studies for this question.

1 finding from 1 review

Screening programmes for the early detection and prevention of oral cancer 2013 · Cochrane All outcomes
There was no evidence to support the use of adjunctive technologies like toluidine blue, brush biopsy or fluorescence imaging as a screening tool to reduce oral cancer mortality; no eligible randomised controlled trial…
0 studies
No studies found

Transbuccal miniplate combined with intraoral approach vs Intraoral approach alone

Wound dehiscence · Adults with fractures of the mandibular angle

Transbuccal miniplate combined with intraoral approach led to lower wound dehiscence compared with intraoral approach alone; GRADE not reported.

1 finding from 1 review

Interventions for the management of mandibular fractures 2013 · Cochrane All outcomes
3 months · Angle of mandible only
RR 0.43 [0.19, 0.98]
1 study · 138 participants
GRADE not reported

Dental repositioning vs Spontaneous re-eruption, orthodontic repositioning, or surgical repositioning

Outcome not reported · Patients (mainly children and young adults) with a history of dental trauma and a diagnosis of luxation (intrusion, extrusion, or lateral…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth 2013 · Cochrane All outcomes
Minimum 12 months follow-up
Types of dental repositioning: to compare spontaneous re-eruption, orthodontic repositioning or surgical repositioning. Main results: No randomised or quasi-randomised controlled trials were found; no study was…
0 studies
No studies found