Cochrane · intervention · CD003878
Interventions for replacing missing teeth: different times for loading dental implants
Esposito, M, Grusovin, MG, Maghaireh, H, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library
Full textEvery question was extracted from the full review (methods and results), not only its Summary of Findings table.
Questions
13
current version
GRADE rated
3
No studies
1
Included studies
26
as reported
No studies 1 · 7.7%Ungraded 9 · 69.2%Very low 3 · 23.1%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Patients who are having osseointegrated root-form dental implants | Edentulous and partially edentulous jaws, adults only (n=1217 participants, 2120 implants in 26 trials) |
| Intervention | (1) Same implants loaded at different times (immediate/early/conventional); (2) same implants occlusally vs non-occlusally loaded during osseointegration; (3) same implants directly vs progressively loaded | Immediate loading; Early loading; Occlusal loading (26 trials; 2120 implants total) |
| Comparison | Conventional loading; Early loading; Immediate loading; Non-occlusal loading; Direct loading | Conventional loading; Early loading; Non-occlusal loading |
| Outcomes | Prosthesis failure if secondary to implant failure; Implant failures (implant mobility and removal of stable implants dictated by progressive marginal bone loss); Radiographic marginal bone level changes on intraoral radiographs taken with a parallel technique | Prosthesis failure (n=26 trials); Implant failure (n=26 trials); Marginal bone level changes (approx 14 trials) |
| Study designs | RCTs of parallel-group and split-mouth design of root-form osseointegrated dental implants with a follow-up of 4 months to 1 year after loading | RCTs, parallel-group and split-mouth design (26 trials) |
| Timing | Follow-up of 4 months to 1 year after loading | 1 year (6-9 months data used for Oh 2006 and Cannizzaro 2008d; longer data used for some radiographs) |
Search date: 2012-06. Databases: Cochrane Oral Health Group's Trials Register; Cochrane Central Register of Controlled Trials (CENTRAL); MEDLINE; EMBASE
Questions and results
Show all 5 versionsImmediate loading vs Conventional loading
Population: Patients who are having osseointegrated root-form dental implants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Implant failure 1 year | RR 1.50 [0.60, 3.77] | 10 studies | Ungraded |
Prosthesis failure 1 year | RR 1.90 [0.67, 5.34] 9 [-3, 43] more per 1000 | 8 studies · 381 participants | Very low Downgraded: risk of bias, publication bias |
Marginal bone level changes 1 year | MD -0.10 [-0.20, -0.01] | 9 studies | Ungraded |
Early loading vs Conventional loading
Population: Patients who are having osseointegrated root-form dental implants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Implant failure 1 year | RR 1.55 [0.46, 5.18] | 2 studies | Ungraded |
Marginal bone level changes 1 year | MD -0.04 [-0.15, 0.07] | 2 studies | Ungraded |
Prosthesis failure 1 year | RR 5.00 [0.63, 39.67] 40 [-4, 387] more per 1000 | 1 study · 48 participants | Very low Downgraded: risk of bias, publication bias |
Immediate loading vs Early loading
Population: Patients who are having osseointegrated root-form dental implants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Prosthesis failure 1 year | RR 0.69 [0.25, 1.87] -15 [-37, 44] fewer per 1000 | 4 studies · 408 participants | Very low Downgraded: risk of bias, publication bias |
Marginal bone level changes 1 year | MD -0.06 [-0.16, 0.03] | 3 studies | Ungraded |
Implant failure 1 year | RR 0.65 [0.26, 1.64] | 5 studies | Ungraded |
Occlusal loading vs Non-occlusal loading
Population: Patients who are having osseointegrated root-form dental implants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Implant failure 1 year | RR 1.00 [0.31, 3.22] | 2 studies | Ungraded |
Prosthesis failure 1 year | RR 1.00 [0.31, 3.22] | 2 studies | Ungraded |
Marginal bone level changes 1 year | MD 0.03 [-0.10, 0.15] | 2 studies | Ungraded |
Progressive loading vs Direct loading
Population: Patients who are having osseointegrated root-form dental implants
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Outcome NR 1 year | Progressive loading (direct vs progressive): no trial could be included; we did not identify any trials which evaluated progressive loading of implants. | 0 studies | No studies |