Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

436 questions · 451 findings · 96 reviews · Headline outcomes only

No studies found 31 · 6.9%GRADE not reported 17 · 3.8%Very low 149 · 33%Low 130 · 28.8%Moderate 103 · 22.8%High 21 · 4.7%

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Quality of life · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Adverse effects ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes adverse effects ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Clinical recurrence (until week 102) · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes clinical recurrence (until week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Endoscopic recurrence · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes endoscopic recurrence (at week 102) compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Initiation of prophylactic therapy guided by colonoscopy vs initiation of prophylactic therapy immediately after surgery

Surgical recurrence ( · adult participants (> 16 years of age) undergoing intestinal resection due to Crohn's disease

It is very uncertain whether initiation of prophylactic therapy guided by colonoscopy changes surgical recurrence ( compared with initiation of prophylactic therapy immediately after surgery (very low certainty).

1 finding from 1 review

Cognitive training vs alternative treatment immediately post intervention

Participant burden (retention rates) · people with mild to moderate dementia

It is very uncertain whether cognitive training changes participant burden (retention rates) compared with alternative treatment immediately post intervention (very low certainty).

1 finding from 1 review

Intervention not reported

HIV infection status of the child · HIV‐positive women during pregnancy and immediate postpartum period

The intervention showed no clear difference in HIV infection status of the child (moderate certainty).

1 finding from 1 review

Intervention not reported

Mean birthweight · HIV‐positive women during pregnancy and immediate postpartum period

The intervention showed no clear difference in mean birthweight (low certainty).

1 finding from 1 review