Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

957 questions · 979 findings · 250 reviews

No studies found 159 · 16.2%GRADE not reported 75 · 7.7%Very low 264 · 27%Low 303 · 30.9%Moderate 138 · 14.1%High 40 · 4.1%

Group B cognitive behavioural therapy: cognitive behavioural therapy + risperidone vs placebo and cognitive and behavioural therapies

Adverse effects: specific ‐ doctors' assessment of adverse effects UKU (events) Medium‐term · people in the prodromal stage of psychosis

It is very uncertain whether group B cognitive behavioural therapy: cognitive behavioural therapy… changes adverse effects: specific ‐ doctors' assessment of adverse effects… compared with cognitive behavioural therapy + placebo (very low certainty).

1 finding from 1 review

Group C cognitive behavioural therapy: cognitive behavioural therapy + placebo vs placebo or supportive treatment

Adverse effects: specific ‐ doctors' assessment of adverse effects UKU (events) Medium‐term · people in the prodromal stage of psychosis

It is very uncertain whether group C cognitive behavioural therapy: cognitive behavioural therapy… changes adverse effects: specific ‐ doctors' assessment of adverse effects… compared with supportive therapy + placebo (very low certainty).

1 finding from 1 review

Group C cognitive behavioural therapy: cognitive behavioural therapy + risperidone vs placebo or supportive treatment

Adverse effects: specific ‐ doctors' assessment of adverse effects UKU (events) Medium‐term · people in the prodromal stage of psychosis

It is very uncertain whether group C cognitive behavioural therapy: cognitive behavioural therapy… changes adverse effects: doctors' assessment of adverse effects UKU (events)… compared with supportive therapy + placebo (very low certainty).

1 finding from 1 review

Open surgical excision vs eccentric exercises

Participant global assessment of success (People who perceived their pain as none) · adult participants with patellar tendinopathy

Open surgical excision showed no clear difference in participant global assessment of success (People who perceived their… compared with eccentric exercises (low certainty).

1 finding from 1 review

Surgery vs non‐surgical treatment

Global assessment of treatment success · people with full‐thickness rotator cuff tears

Surgery showed no clear difference in participant‐rated global assessment of treatment success at 12 months compared with non‐operative treatment (low certainty).

1 finding from 1 review

Miswak (Salvadora persica) stick vs Chlorhexidine mouthwash

Patient self-assessment VAS (scale 0 to 10) · Adolescents and adults aged over 16 years with clinical or self-assessed halitosis of oral origin; excluding induced or physiological…

It is very uncertain whether miswak (Salvadora persica) stick changes patient self-assessment VAS (scale 0 to 10) compared with chlorhexidine mouthwash (very low certainty).

1 finding from 1 review

Inactivated influenza vaccine vs placebo or no intervention

Nausea or vomiting assessed by subjective report Timing of assessment: single influenza season · healthy adults

Inactivated parenteral influenza vaccine showed no clear difference in nausea or vomiting assessed by subjective report Timing of… compared with placebo or 'do nothing' (low certainty).

1 finding from 1 review

Primary care professionals vs ordinary emergency department physicians

Time from arrival to clinical assessment and treatment · patients with minor injuries and illnesses

It is very uncertain whether primary care professionals changes time from arrival to clinical assessment and treatment compared with ordinary emergency department physicians (very low certainty).

1 finding from 1 review