Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,771 questions · 10,185 findings · 893 reviews

No studies found 2,109 · 20.7%GRADE not reported 1,125 · 11%Very low 2,279 · 22.4%Low 2,514 · 24.7%Moderate 1,709 · 16.8%High 449 · 4.4%

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Suprasorb CNP system vs the ABThera system

Proportion of participants with successful primary fascial closure of the abdomen · adults with an open abdomen after surgery who have not experienced trauma

It is very uncertain whether suprasorb CNP system changes proportion of participants with successful primary fascial closure… compared with the ABThera system (very low certainty).

1 finding from 1 review

Suprasorb CNP system vs the ABThera system

Adverse events (fistulae formation) · adults with an open abdomen after surgery who have not experienced trauma

It is very uncertain whether suprasorb CNP system changes adverse events (fistulae formation) compared with the ABThera system (very low certainty).

1 finding from 1 review

Amoxicillin + metronidazole + SRP vs Supragingival scaling (plus placebo)

All‐cause death · People with periodontitis and metabolic syndrome (no CVD; primary prevention)

It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all-cause death compared with supragingival scaling (plus placebo) (very low certainty).

1 finding from 1 review

Composite resin with a beveled cavity margin vs Composite resin with no bevel (butt-joint margin)

Restoration failure · Children with carious primary teeth

No comparative effect estimate was reported; no bevel had twice the failure rate in the review narrative.

1 finding from 1 review

Hall technique vs Compomer restoration or non-restorative caries treatment

Restoration failure · Children with carious primary teeth

No comparative effect estimate was reported; the review reports this three-arm comparison but tabulates only compomer failure.

1 finding from 1 review

Metal-free single crowns (full-contour zirconia) vs Composite strip crown

Restoration failure · Children with carious primary teeth

No comparative effect estimate was reported; failure rates were 3.3% and 15%.

1 finding from 1 review

Composite resin with etch-and-rinse (total-etch) adhesion vs Composite resin with self-etch adhesion (same universal adhesive)

Restoration failure · Children with carious primary teeth

No comparative effect estimate was reported; etch-and-rinse had a higher tabulated failure rate.

1 finding from 1 review

Composite resin vs High-viscosity GIC and bulk-fill composite resins

Restoration failure · Children with carious primary teeth

No comparative effect estimate was reported; tabulated failure rates ranged from 0% to 2.9%.

1 finding from 1 review

Periodontal treatment: scaling and root planing (SRP) plus advice vs Community care: advice only

Serum high-sensitivity C-reactive protein (hs-CRP) · Patients with cardiovascular disease and chronic periodontitis
1 finding from 1 review

Glass carbomer vs Resin-modified glass-ionomer cement + composite resin (modified open-sandwich restoration)

Restoration failure · Children with carious primary teeth

No comparative effect estimate was reported; glass carbomer had the highest tabulated failure range.

1 finding from 1 review

GIC with cavity conditioner vs GIC without cavity conditioner

Restoration failure · Children with carious primary teeth

No comparative effect estimate was reported; the review states cavity conditioner did not improve success.

1 finding from 1 review

HVGIC bilayer insertion and surface coating protocols vs Alternative HVGIC insertion and surface coating protocols

Restoration failure · Children with carious primary teeth

No comparative effect estimate was reported; bilayer placement and nanofilled coating were described as improving survival.

1 finding from 1 review

Er,Cr:YSGG laser (erbium,chromium:yttrium-scandium-gallium-garnet) vs Placebo (placebo laser or placebo agent) or no treatment

Changes in intensity of pain (VAS 0 to 10) tested through air blast stimuli · Patients aged above 12 years with self-reported tooth hypersensitivity confirmed on clinical evaluation

Er,Cr:YSGG laser (erbium,chromium:yttrium-scandium-gallium-garnet) led to lower changes in intensity of pain (VAS 0 to 10) tested through air blast… compared with placebo (placebo laser or placebo agent) or no treatment; GRADE not reported.

3 findings from 1 review