What do systematic reviews say?

Brief intervention vs brief advice, information, or assessment only

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 5380 participants
  Very low

Other psychosocial intervention vs usual care, brief intervention, or wait list

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 2106 participants
  Very low

Other psychosocial intervention vs usual care, brief intervention, or wait list

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 1664 participants
  Very low

Pharmacologic intervention vs placebo

Pharmacologic intervention showed no clear difference in retention compared with placebo (low certainty).

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 1.13 [0.89, 1.44]
  3 studies · 247 participants
  Low

Any Psychosocial intervention plus pharm vs psychosocial interventions

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 475 participants
  Low
• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 0.62 [0.16, 2.47]
  1 study · 102 participants
  Very low

Any Psychosocial intervention plus pharm vs psychosocial interventions

Pharmacologic intervention along with psychosocial intervention showed no clear difference in retention compared with psychosocial intervention alone (moderate certainty).

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 1.15 [0.95, 1.4]
  3 studies · 363 participants
  Moderate

Pharmacologic intervention vs another pharmacologic intervention

The review found no eligible studies for this question.

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Pharmacologic intervention vs another pharmacologic intervention

Pharmacologic intervention showed no clear difference in retention compared with another pharmacologic intervention (low certainty).

• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 0.95 [0.76, 1.19]
  2 studies · 190 participants
  Low
• Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
  RR 1.02 [0.96, 1.08]
  2 studies · 200 participants
  Low

Intervention not reported

The intervention showed no clear difference in mg/day LDL cholesterol (high certainty).

• Pravastatin for lowering lipids 2023 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 765 participants
  High

Intervention not reported

The intervention showed no clear difference in mg/day LDL cholesterol (moderate certainty).

• Pravastatin for lowering lipids 2023 · Cochrane Headline outcomes only
  no estimate extracted
  22 studies · 3117 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in mg/day LDL cholesterol (moderate certainty).

• Pravastatin for lowering lipids 2023 · Cochrane Headline outcomes only
  no estimate extracted
  35 studies · 4869 participants
  Moderate

Intervention not reported

The intervention showed no clear difference in mg/day LDL cholesterol (high certainty).

• Pravastatin for lowering lipids 2023 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 881 participants
  High

Intervention not reported

The review found no eligible studies for this question.

• Pravastatin for lowering lipids 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

It is very uncertain whether the intervention changes WDAEs (very low certainty).

• Pravastatin for lowering lipids 2023 · Cochrane Headline outcomes only
  RR 0.81 [0.63, 1.03]
  33 studies · 6187 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 283 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 112 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  22 studies · 917 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  19 studies · 535 participants
  Low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 111 participants
  Very low

Intervention not reported

• Trunk training following stroke 2023 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 378 participants
  Low