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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,000 questions in 69 reviews · Urology

current versions
No studies 196 · 19.6%Ungraded 33 · 3.3%Very low 198 · 19.8%Low 354 · 35.4%Moderate 206 · 20.6%High 13 · 1.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Single‐dose, preoperative MMC‐EMDA vs TURBT alone
Time to progression
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
HR 0.74 [0, 247.93]1 study · 233 participantsVery low
Single‐dose, preoperative MMC‐EMDA vs TURBT alone
Serious adverse events
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
RR 1.74 [0.52, 5.77]1 study · 233 participantsVery low
Single‐dose, preoperative MMC‐EMDA vs TURBT alone
Disease‐specific survival
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
HR 1.06 [0.8, 1.4]1 study · 233 participantsModerate
Single‐dose, preoperative MMC‐EMDA vs TURBT alone
Disease‐specific quality of life ‐ not reported
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
no estimate extractedNRNo studies
Postoperative MMC‐EMDA induction vs postoperative BCG induction therapy
Serious adverse events
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
RR 0.75 [0.18, 3.11]1 study · 72 participantsVery low
Postoperative MMC‐EMDA induction vs postoperative BCG induction therapy
Disease‐specific survival
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
no estimate extracted1 study · 72 participantsLow
Postoperative MMC‐EMDA induction vs postoperative BCG induction therapy
Disease‐specific quality of life ‐ not reported
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
no estimate extractedNRNo studies
Postoperative MMC‐EMDA induction vs MMC‐PD induction therapy
Time to recurrence
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
RR 0.65 [0.44, 0.98]1 study · 72 participantsLow
Postoperative MMC‐EMDA induction vs MMC‐PD induction therapy
Time to progression
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
no estimate extracted1 study · 72 participantsLow
Postoperative MMC‐EMDA induction vs MMC‐PD induction therapy
Serious adverse events
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
RR 1.5 [0.27, 8.45]1 study · 72 participantsVery low
Postoperative MMC‐EMDA induction vs MMC‐PD induction therapy
Disease‐specific survival
Intravesical electromotive drug administration for non‐muscle invasive bladder cancer (2017) · Cochrane
no estimate extracted1 study · 72 participantsLow
Partial nephrectomy vs radical nephrectomy
Time‐to‐death of any cause (anticipated absolute effects refer to all‐cause mortality; median
Partial nephrectomy versus radical nephrectomy for clinical localised renal masses (2017) · Cochrane
HR 1.5 [1.03, 2.18]1 study · 541 participantsLow
Partial nephrectomy vs radical nephrectomy
Serious adverse events (Surgery‐related mortality)
Partial nephrectomy versus radical nephrectomy for clinical localised renal masses (2017) · Cochrane
RR 2.04 [0.19, 22.34]1 study · 541 participantsLow
Partial nephrectomy vs radical nephrectomy
Time‐to‐recurrence (anticipated absolute effects refer to recurrence; median
Partial nephrectomy versus radical nephrectomy for clinical localised renal masses (2017) · Cochrane
HR 1.37 [0.58, 3.24]1 study · 541 participantsLow
Partial nephrectomy vs radical nephrectomy
Permanent haemodialysis ‐ not measured
Partial nephrectomy versus radical nephrectomy for clinical localised renal masses (2017) · Cochrane
no estimate extractedNRNo studies
Partial nephrectomy vs radical nephrectomy
Quality of Life ‐ not measured
Partial nephrectomy versus radical nephrectomy for clinical localised renal masses (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs placebo
Number of nocturnal voids
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted6 studies · 1982 participantsLow
Desmopressin vs placebo
Major adverse events
Desmopressin for treating nocturia in men (2017) · Cochrane
RR 3.05 [0.13, 73.39]1 study · 115 participantsLow
Desmopressin vs placebo
Duration of first sleep episode
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted1 study · 115 participantsModerate
Desmopressin vs placebo
Time to first void ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs placebo
Minor adverse events
Desmopressin for treating nocturia in men (2017) · Cochrane
RR 0.86 [0.49, 1.49]1 study · 115 participantsLow
Desmopressin vs placebo
Treatment withdrawal due to adverse event
Desmopressin for treating nocturia in men (2017) · Cochrane
RR 3.05 [0.13, 73.39]1 study · 115 participantsLow
Desmopressin vs behaviour modifications
Number of nocturnal voids ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs behaviour modifications
Quality of life ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs behaviour modifications
Major adverse events ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs behaviour modifications
Duration of first sleep episode
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted1 study · 60 participantsLow
Desmopressin vs behaviour modifications
Time to first void ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs placebo
Quality of life ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs behaviour modifications
Minor adverse events ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs behaviour modifications
Treatment withdrawal due to adverse event ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs alpha‐blocker
Number of nocturnal voids
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted1 study · 31 participantsModerate
Desmopressin vs alpha‐blocker
Quality of life
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted1 study · 31 participantsModerate
Desmopressin vs alpha‐blocker
Major adverse events
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted1 study · 31 participantsLow
Desmopressin vs alpha‐blocker
Duration of first sleep episode ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs alpha‐blocker
Time to first void ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs alpha‐blocker
Minor adverse events
Desmopressin for treating nocturia in men (2017) · Cochrane
RR 1.07 [0.07, 15.57]1 study · 31 participantsVery low
Desmopressin vs alpha‐blocker
Treatment withdrawal due to adverse event
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted1 study · 31 participantsLow
Desmopressin plus alpha‐blocker vs alpha‐blocker
Number of nocturnal voids
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted3 studies · 341 participantsModerate
Desmopressin vs placebo
Major adverse events
Desmopressin for treating nocturia in men (2017) · Cochrane
RR 0.97 [0.1, 9.03]2 studies · 536 participantsVery low
Desmopressin plus alpha‐blocker vs alpha‐blocker
Quality of life
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted3 studies · 341 participantsModerate
Desmopressin plus alpha‐blocker vs alpha‐blocker
Major adverse events
Desmopressin for treating nocturia in men (2017) · Cochrane
RR 0.3 [0.01, 7.32]3 studies · 402 participantsLow
Desmopressin plus alpha‐blocker vs alpha‐blocker
Duration of first sleep episode ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin plus alpha‐blocker vs alpha‐blocker
Time to first void ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin plus alpha‐blocker vs alpha‐blocker
Minor adverse events
Desmopressin for treating nocturia in men (2017) · Cochrane
RR 1.6 [0.15, 16.82]3 studies · 402 participantsVery low
Desmopressin plus alpha‐blocker vs alpha‐blocker
Treatment withdrawal due to adverse event
Desmopressin for treating nocturia in men (2017) · Cochrane
RR 2.84 [0.46, 17.66]3 studies · 402 participantsLow
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Number of nocturnal voids
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted1 study · 405 participantsModerate
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Quality of life ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Major adverse events
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted1 study · 427 participantsLow
Desmopressin plus alpha‐blocker vs alpha‐blocker plus anticholinergic
Duration of first sleep episode ‐ not reported
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extractedNRNo studies
Desmopressin vs placebo
Duration of first sleep episode
Desmopressin for treating nocturia in men (2017) · Cochrane
no estimate extracted4 studies · 652 participantsVery low