What do systematic reviews say?

One type of repeat midurethral tape vs another type of repeat midurethral tape

The review found no eligible studies for this question.

• Interventions for treating recurrent stress urinary incontinence after failed minimally invasive synthetic midurethral… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Repeat midurethral tape (any type) vs any other non‐tape surgical treatment (e.g. traditional sling, colposuspension, injectables)

The review found no eligible studies for this question.

• Interventions for treating recurrent stress urinary incontinence after failed minimally invasive synthetic midurethral… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Gore‐Tex vs Ethibond

Gore‐Tex showed no clear difference in functional success of the surgery compared with ethibond (low certainty).

• Types of materials for frontalis sling surgery for congenital ptosis 2019 · Cochrane Headline outcomes only
  RR 1.12 [0.93, 1.35]
  1 study · 60 participants
  Low

Mersilene mesh vs autogenous fascia

The review found no eligible studies for this question.

• Types of materials for frontalis sling surgery for congenital ptosis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Mersilene mesh vs autogenous fascia

• Types of materials for frontalis sling surgery for congenital ptosis 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  Very low

Gore‐Tex vs Ethibond

Gore‐Tex showed no clear difference in recurrence after surgery compared with ethibond (low certainty).

• Types of materials for frontalis sling surgery for congenital ptosis 2019 · Cochrane Headline outcomes only
  RR 0.33 [0.01, 6.64]
  1 study · 60 participants
  Low

Autogenous fascia vs Gore‐Tex

Autogenous fascia showed no clear difference in recurrence after surgery compared with gore‐Tex (low certainty).

• Types of materials for frontalis sling surgery for congenital ptosis 2019 · Cochrane Headline outcomes only
  RR 0.5 [0.12, 1.8]
  1 study · 110 participants
  Low

Thromboelastography threshold vs standard of care (laboratory parameters)

The review found no eligible studies for this question.

• Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Perioperative restrictive fluid therapy vs goal‐directed fluid therapy

It is very uncertain whether perioperative restrictive fluid therapy changes surgery‐related complications (during longest compared with goal‐directed fluid therapy (very low certainty).

• Perioperative restrictive versus goal‐directed fluid therapy for adults undergoing major non‐cardiac surgery 2019 · Cochrane Headline outcomes only
  RR 1.54 [0.87, 2.72]
  4 studies · 364 participants
  Very low

Perioperative restrictive fluid therapy vs goal‐directed fluid therapy

It is very uncertain whether perioperative restrictive fluid therapy changes non‐surgery‐related complications (during longest compared with goal‐directed fluid therapy (very low certainty).

• Perioperative restrictive versus goal‐directed fluid therapy for adults undergoing major non‐cardiac surgery 2019 · Cochrane Headline outcomes only
  RR 1 [0.52, 1.93]
  1 study · 74 participants
  Very low

Epidural analgesia vs systemic analgesia

Epidural analgesia showed no clear difference in vomiting up to 48 hours after surgery compared with systemic analgesia (low certainty).

• Postoperative epidural analgesia versus systemic analgesia for thoraco‐lumbar spine surgery in children 2019 · Cochrane Headline outcomes only
  RR 0.87 [0.58, 1.3]
  6 studies · 215 participants
  Low

Preoperative radiotherapy vs surgery

Preoperative radiotherapy may leads to higher postoperative morbidity ‐ sepsis (within 30 days after surgery) compared with surgery alone (low certainty).

• Preoperative radiotherapy and curative surgery for the management of localised rectal carcinoma 2018 · Cochrane Headline outcomes only
  RR 1.25 [1.04, 1.52]
  2 studies · 2698 participants
  Low

Preoperative radiotherapy vs surgery

Preoperative radiotherapy may leads to higher postoperative morbidity ‐ surgical complications (within 30 days… compared with surgery alone (low certainty).

• Preoperative radiotherapy and curative surgery for the management of localised rectal carcinoma 2018 · Cochrane Headline outcomes only
  RR 1.2 [1.01, 1.42]
  2 studies · 2698 participants
  Low

Alpha2‐adrenergic agonist vs control

• Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
  no estimate extracted
  16 studies · 14081 participants
  High

Alpha2‐adrenergic agonist vs control

Alpha‐2 adrenergic agonists may leads to lower acute stroke (within 30‐days after surgery: new focal neurologic… compared with control (low certainty).

• Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
  RR 0.37 [0.15, 0.93]
  7 studies · 1175 participants
  Low

Alpha2‐adrenergic agonist vs control

• Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 12525 participants
  High

Alpha2‐adrenergic agonist vs control

• Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
  no estimate extracted
  12 studies · 13907 participants
  Moderate

Alpha2‐adrenergic agonist vs control

• Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 11542 participants
  High

Alpha2‐adrenergic agonist vs control

Alpha‐2 adrenergic agonists showed no clear difference in all‐cause mortality (within 30‐days after surgery: any reported death) compared with control (moderate certainty).

• Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
  RR 0.52 [0.26, 1.04]
  16 studies · 1947 participants
  Moderate

Alpha2‐adrenergic agonist vs control

• Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 22 participants
  GRADE not reported