Mortality Mortality at latest · liver transplant recipients
T‐cell antibody induction may leads to lower mortality Mortality at latest compared with placebo/no intervention (low certainty).
1 finding from 1 review
Graft loss including death · liver transplant recipients
T‐cell antibody induction may leads to lower graft loss including death Graft loss including death at latest compared with placebo/no intervention (low certainty).
1 finding from 1 review
Acute rejection · liver transplant recipients
T‐cell antibody induction probably leads to lower acute rejection Number of participants who experienced at least 1… compared with placebo/no intervention (moderate certainty).
1 finding from 1 review
All‐cause mortality · patients with primary biliary cirrhosis.
It is very uncertain whether ursodeoxycholic acid changes all‐cause mortality compared with placebo or no intervention (very low certainty).
1 finding from 1 review
All‐cause mortality or liver transplantation · patients with primary biliary cirrhosis.
It is very uncertain whether ursodeoxycholic acid changes all‐cause mortality or liver transplantation compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Serious adverse events · patients with primary biliary cirrhosis.
It is very uncertain whether ursodeoxycholic acid changes serious adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Non‐serious adverse events · patients with primary biliary cirrhosis.
It is very uncertain whether ursodeoxycholic acid changes non‐serious adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Pruritus · patients with primary biliary cirrhosis.
Ursodeoxycholic acid showed no clear difference in pruritus compared with placebo or no intervention (low certainty).
1 finding from 1 review
Bilirubin (µmol/L) · patients with primary biliary cirrhosis.
1 finding from 1 review
Liver biopsy findings (worsening of histological stage) · patients with primary biliary cirrhosis.
It is very uncertain whether ursodeoxycholic acid changes liver biopsy findings (worsening of histological stage) compared with placebo or no intervention (very low certainty).
1 finding from 1 review
All‐cause mortality · patients with primary biliary cirrhosis.
It is very uncertain whether bezafibrate changes all‐cause mortality compared with no intervention (very low certainty).
1 finding from 1 review
Liver morbidity · patients with primary biliary cirrhosis.
It is very uncertain whether bezafibrate changes liver morbidity compared with no intervention (very low certainty).
1 finding from 1 review
Adverse events · patients with primary biliary cirrhosis.
It is very uncertain whether bezafibrate changes adverse events compared with no intervention (very low certainty).
1 finding from 1 review
Alkaline phosphatase · patients with primary biliary cirrhosis.
3 findings from 1 review
no estimate extracted
4 studies · 79 participants
Low
no estimate extracted
2 studies · 38 participants
Very low
no estimate extracted
2 studies · 41 participants
Low
Maximum total serum bilirubin (µmol/L); all studies · patients with primary biliary cirrhosis.
1 finding from 1 review
All‐cause mortality · patients with primary biliary cirrhosis.
It is very uncertain whether bisphosphonates changes all‐cause mortality compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Fracture · patients with primary biliary cirrhosis.
It is very uncertain whether bisphosphonates changes fractures compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Adverse events · patients with primary biliary cirrhosis.
It is very uncertain whether bisphosphonates changes adverse events compared with placebo or no intervention (very low certainty).
1 finding from 1 review
Lumbar spine bone mineral density (BMD) · patients with primary biliary cirrhosis.
1 finding from 1 review
Hip/femoral bone mineral density (BMD) · patients with primary biliary cirrhosis.
1 finding from 1 review