Ursodeoxycholic acid vs placebo or no intervention: Liver biopsy findings (worsening of histological stage)
It is very uncertain whether ursodeoxycholic acid changes liver biopsy findings (worsening of histological stage) compared with placebo or no intervention (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Ursodeoxycholic acid vs placebo or no intervention Liver biopsy findings (worsening of histological stage) · patients with primary biliary cirrhosis. It is very uncertain whether ursodeoxycholic acid changes liver biopsy findings (worsening of histological stage) compared with placebo or no intervention (very low certainty). Ursodeoxycholic acid for primary biliary cirrhosis (2012) · Cochrane Headline outcomes only | RR 0.62 [0.44, 0.88] | 7 studies · 551 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Ursodeoxycholic acid for primary biliary cirrhosis 2012 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.