Quality of Life: SF‐36 (physical component) · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Health‐related quality of life (mental) · participants with painful obstructive chronic pancreatitis
1 finding from 1 review
Endocrine pancreatic insufficiency (new onset) ‐ long‐term · participants with painful obstructive chronic pancreatitis
Endoscopy showed no clear difference in endocrine pancreatic insufficiency (new onset) ‐ long‐term compared with surgery (low certainty).
1 finding from 1 review
Exocrine pancreatic insufficiency (new onset) · participants with painful obstructive chronic pancreatitis
Endoscopy showed no clear difference in exocrine pancreatic insufficiency (new onset) ‐ long‐term compared with surgery (moderate certainty).
1 finding from 1 review
Overall survival (3 years) · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery
It is very uncertain whether combination chemotherapy changes overall survival (3 years) compared with single‐agent chemotherapy (very low certainty).
1 finding from 1 review
Disease-free survival · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery
It is very uncertain whether combination chemotherapy changes disease‐free survival (3 years) compared with single‐agent chemotherapy (very low certainty).
1 finding from 1 review
Complete response rate after preoperative chemoradiation (ypCR) · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery
Combination chemotherapy leads to higher complete response rate after preoperative chemoradiation (ypCR) compared with single‐agent chemotherapy (high certainty).
1 finding from 1 review
Toxicity ‐ early adverse events G3/4 · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery
Combination chemotherapy probably leads to higher toxicity ‐ early adverse events G3/4 compared with single‐agent chemotherapy (moderate certainty).
1 finding from 1 review
Metastases intra‐abdominal · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery
Combination chemotherapy showed no clear difference in metastases intra‐abdominal compared with single‐agent chemotherapy (moderate certainty).
1 finding from 1 review
Radiotherapy compliance · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery
Combination chemotherapy probably leads to lower radiotherapy compliance compared with single‐agent chemotherapy (moderate certainty).
1 finding from 1 review
Chemotherapy compliance · people with resectable stage II and III rectal cancer undergoing preoperative chemoradiation followed by surgery
Combination chemotherapy leads to lower chemotherapy compliance compared with single‐agent chemotherapy (high certainty).
1 finding from 1 review
Intervention not reported
Mortality within the longest · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
The intervention showed no clear difference in mortality within the longest (low certainty).
1 finding from 1 review
Intervention not reported
Mortality within the longest · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
It is very uncertain whether the intervention changes mortality within the longest (very low certainty).
1 finding from 1 review
Intervention not reported
Mortality within 30 days of · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
1 finding from 1 review
Intervention not reported
Mortality within 30 days of · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
1 finding from 1 review
Intervention not reported
Surgical site infection within 30 days in trials with low risk of bias (14 days to 30 days) · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
The intervention showed no clear difference in surgical site infection within 30 days in trials with low risk of… (low certainty).
1 finding from 1 review
Intervention not reported
Surgical site infection within 30 days, irrespective of risk of bias (14 days to 30 days) · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
The intervention showed no clear difference in surgical site infection within 30 days, irrespective of risk of bias… (low certainty).
1 finding from 1 review
Intervention not reported
Respiratory insufficiency · surgical patients with need for abdominal, caesarean section, orthopaedic or breast surgery
The intervention showed no clear difference in respiratory insufficiency (moderate certainty).
1 finding from 1 review
Additional analgesia required (escape analgesia) · children undergoing surgery
Tramadol may leads to lower number of patients requiring rescue analgesia (PACU) compared with placebo (low certainty).
1 finding from 1 review
Number of patients with PONV (PACU) · children undergoing surgery
Tramadol showed no clear difference in number of patients with PONV (PACU) compared with nalbuphine (low certainty).
1 finding from 1 review