Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,520 questions · 1,575 findings · 175 reviews · Headline outcomes only

No studies found 239 · 15.2%GRADE not reported 59 · 3.7%Very low 337 · 21.4%Low 406 · 25.8%Moderate 410 · 26%High 124 · 7.9%

Medial epicondylectomy plus oral steroids vs oral steroids alone

Proportion of ulnar nerves with sensory improvement after one year · patients with nerve damage in leprosy

It is very uncertain whether medial epicondylectomy plus oral steroids changes proportion of ulnar nerves with sensory improvement after one year compared with oral steroids alone (very low certainty).

1 finding from 1 review

Medial epicondylectomy plus oral steroids vs oral steroids alone

Proportion of ulnar nerves with motor improvement after one year · patients with nerve damage in leprosy

It is very uncertain whether medial epicondylectomy plus oral steroids changes proportion of ulnar nerves with motor improvement after one year compared with oral steroids alone (very low certainty).

1 finding from 1 review

Intranasal corticosteroids vs placebo

Health outcomes Peak expiratory flow readings (higher readings indicate better peak flow) · adults and children > 12 with non‐allergic rhinitis

It is very uncertain whether intranasal corticosteroids changes objective measurement of airflow: peak flow rate (expiratory) compared with placebo (very low certainty).

1 finding from 1 review

Adjunctive corticosteroids vs no such treatment

Need for mechanical ventilation · patients with Pneumocystis jiroveci pneumonia and HIV infection

Adjunctive corticosteroids probably leads to lower need for mechanical ventilation at 1 month compared with no such treatment (moderate certainty).

1 finding from 1 review

Corticosteroids vs placebo

Histological improvement (dichotomous) · inactive EoE patients

Corticosteroids probably leads to higher histological improvement (dichotomous) compared with placebo (moderate certainty).

1 finding from 1 review

Corticosteroids vs placebo

Withdrawals due to adverse events · inactive EoE patients

Corticosteroids may leads to lower withdrawals due to adverse events 12 to 50 weeks compared with placebo (low certainty).

1 finding from 1 review