Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

459 questions · 589 findings · 78 reviews · Oral Health

No studies found 64 · 10.9%GRADE not reported 366 · 62.1%Very low 90 · 15.3%Low 49 · 8.3%Moderate 10 · 1.7%High 10 · 1.7%

Primary closure of the extraction socket with a mucoperiosteal flap vs Application of platelet-rich fibrin (PRF) without primary closure

Complications and side effects · People on antiresorptive treatment undergoing tooth extraction (at risk of MRONJ)
1 finding from 1 review

Referral to a specific dental treatment facility vs Generic advice letter to see a dentist

Number of caries in permanent teeth (DT index) · School children, primary school in Saudi Arabia

It is very uncertain whether referral to a specific dental treatment facility changes number of caries in permanent teeth (DT index) compared with generic advice letter to see a dentist (very low certainty).

1 finding from 1 review

Glass ionomer-based sealant vs No sealant (control/no treatment)

Dental caries increment, DMFT/dmft (whole-tooth level) · Children with caries-free primary first molars (with or without caries on other teeth), aged 1-5 years (paediatric clinic/dental school,…
1 finding from 1 review
  • Sealants for preventing dental caries in primary teeth 2022 · Cochrane All outcomes
    12 months
    Joshi 2019: dmft 8.43 (SD 5.84) with sealant vs 10.05 (SD 6.16) with no sealant at 12 months (caries threshold uncertain); Chadwick 2005: no significant difference in caries increment on occlusal surfaces, no summary…
    2 studies
    GRADE not reported

Rubber dam isolation and moisture control (alone or with saliva aspiration) vs Cotton rolls (with or without saliva aspiration)

Restoration survival · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)

Rubber dam isolation and moisture control (alone or with saliva… may leads to higher survival rate of restorations (6 months) compared with cotton rolls (with or without saliva aspiration) (low certainty).

4 findings from 1 review
Show 1 more finding

Rubber dam vs Isolite system

Participant acceptance/satisfaction · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)
1 finding from 1 review
  • Rubber dam isolation for restorative treatment in dental patients 2021 · Cochrane All outcomes
    Pit and fissure sealing (permanent molars)
    Rubber dam may be associated with significantly lower satisfaction than the Isolite system but evidence very uncertain, mainly worse comfort (31%, P=0.02) and less preference (26%, P=0.002) (Alhareky 2014).
    1 study · 42 participants
    Very low

Inflammatory bowel disease (IBD) vs Healthy controls without IBD

Periodontal disease (periodontitis) coincidence · Patients with inflammatory bowel disease (IBD) and controls without IBD; mostly adults (one pediatric study), both sexes

Patients with IBD have about 2.5-fold higher odds of coexisting periodontal disease than healthy controls (pooled OR 2.49, 95% CI 1.97-3.15; 6 studies; not GRADE-rated).

1 finding from 1 review

Rubber dam vs Isolite system

Costs: operation/chair time · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)

It is very uncertain whether rubber dam isolation changes costs: operation/chair time compared with isolite system (very low certainty).

1 finding from 1 review

Rubber dam isolation and moisture control (alone or with saliva aspiration) vs Cotton rolls (with or without saliva aspiration)

Costs: treatment/operation time · Dental patients undergoing direct or indirect restorative treatment (no age or gender restriction)

It is very uncertain whether rubber dam isolation and moisture control (alone or with saliva… changes costs: treatment/operation time compared with cotton rolls (with or without saliva aspiration) (very low certainty).

1 finding from 1 review