Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

974 questions · 987 findings · 137 reviews

No studies found 182 · 18.4%GRADE not reported 90 · 9.1%Very low 165 · 16.7%Low 312 · 31.6%Moderate 163 · 16.5%High 75 · 7.6%

Metabolomics vs non metabolomics

Clinical pregnancy (Presence of a fetal heart on ultrasound scan at seven weeks of gestation) · Women undergoing IVF/ICSI cycles

Metabolomics showed no clear difference in clinical pregnancy (Presence of a fetal heart on ultrasound scan at… compared with non metabolomics (low certainty).

1 finding from 1 review

Discontinued intravenous (IV) oxytocin stimulation vs continued IV oxytocin stimulation

Uterine tachysystole combined with abnormal fetal heart rate · pregnant women in latent phase of labour stimulated with oxytocin for with induction of labour. No exclusion criteria were applied in…

Discontinued intravenous (IV) oxytocin stimulation probably leads to lower uterine tachysystole combined with abnormal fetal heart rate compared with continued IV oxytocin stimulation (moderate certainty).

1 finding from 1 review

Mirtazapine vs placebo

Safety Any serious adverse event · adults with fibromyalgia

It is very uncertain whether mirtazapine changes safety: serious adverse events compared with placebo (very low certainty).

1 finding from 1 review

Periodontal treatment (scaling and root planing, alone or with antimicrobials) vs Alternative (less intensive) periodontal treatment, alone or with placebo

Perinatal mortality · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination

It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes perinatal mortality (including fetal and neonatal deaths up to the… compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).

1 finding from 1 review

Intervention not reported

Leukopenia** grade 3 or 4 (safety population) · women with metastatic breast cancer

The intervention probably leads to higher leukopenia** grade 3 or 4 (safety population) (moderate certainty).

1 finding from 1 review

Intervention not reported

Nausea/vomiting* grade 3 or 4 (safety population) by type of platinum agent in platinum regimen · women with metastatic breast cancer

The intervention probably leads to lower nausea/vomiting* grade 3 or 4 (safety population) by type of… (moderate certainty).

1 finding from 1 review

Intervention not reported

Anaemia grade 3 or 4 (safety population) by type of platinum agent in platinum regimen · women with metastatic breast cancer

The intervention leads to higher anaemia grade 3 or 4 (safety population) by type of platinum agent… (high certainty).

1 finding from 1 review

Intervention not reported

Hair loss grade 3 or 4 (safety population) · women with metastatic breast cancer

The intervention leads to higher hair loss grade 3 or 4 (safety population) (high certainty).

1 finding from 1 review

Vaginal PGE₂ vs placebo or expectant management

Uterine hyperstimulation (fetal heart rate changes unclear) · patients with induction of labour at term

Vaginal PGE₂ showed no clear difference in uterine hyperstimulation (fetal heart rate changes unclear) compared with placebo or expectant management (low certainty).

1 finding from 1 review

Foley catheter vs intravenous (IV) oxytocin

Uterine hyperstimulation with fetal heart rate changes · pregnant women with a previous low transverse caesarean section, singleton live pregnancy with cephalic presentation, period of gestation…

Foley catheter showed no clear difference in uterine hyperstimulation with fetal heart rate changes compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review