Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,773 questions · 1,817 findings · 212 reviews · Headline outcomes only

No studies found 383 · 21.1%GRADE not reported 192 · 10.6%Very low 472 · 26%Low 444 · 24.4%Moderate 228 · 12.5%High 98 · 5.4%

Second‐generation endometrial ablation vs first‐generation endometrial ablation

Proportion given local anaesthesia (%) · heavy menstrual bleeding

It is very uncertain whether overall analyses: second‐generation endometrial ablation changes proportion given local anaesthesia (%) compared with first‐generation endometrial ablation (very low certainty).

1 finding from 1 review

Intervention not reported

Acute chest syndrome ( · patients with avascular necrosis in people with sickle cell disease

It is very uncertain whether the intervention changes acute chest syndrome ( (very low certainty).

1 finding from 1 review

Respiratory muscle training vs breathing exercises

Number of unscheduled hospitalizations for episodes of chest infection or acute exacerbation of chronic respiratory failure within 1 year of randomization · participants with limb‐girdle muscular dystrophy or Becker muscular dystrophy

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Pain: 50% reduction in headache frequency Post‐treatment Lower scores = fewer headaches · Children and adolescents with chronic pain

It is very uncertain whether the intervention changes pain: 50% reduction in headache frequency Post‐treatment Lower… (very low certainty).

1 finding from 1 review

Other dressing vs control

Proportion of participants developing a new pressure ulcer · individuals at risk of pressure ulcer development

It is very uncertain whether other dressing changes pressure ulcer incidence: adhesive foam dressing vs no dressing compared with control (very low certainty).

1 finding from 1 review

Percutaneous surgery vs steroid injection

Adverse events (infection, partial loss of movement, tendon or −0 injury, dysaesthesia, and skin atrophy or hypopigmentation) · patients with trigger finger

It is very uncertain whether percutaneous surgery changes adverse events (infection, partial loss of movement, tendon or −0… compared with steroid injection (very low certainty).

1 finding from 1 review

Endoscopic surgery vs open surgery

Adverse events (infection, dysaesthesia) · patients with trigger finger

It is very uncertain whether endoscopic surgery changes adverse events (infection, dysaesthesia) compared with open surgery (very low certainty).

1 finding from 1 review