Cochrane · systematic review · CD011711
Respiratory muscle training in children and adults with neuromuscular disease
Silva, IS, Pedrosa, R, Azevedo, IG, et al. · Cochrane Database of Systematic Reviews · 2019 · Cochrane Library
NeuromuscularAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
35
current version
GRADE rated
10
No studies
25
Included studies
NR
No studies 25 · 71.4%Ungraded 0 · 0%Very low 3 · 8.6%Low 7 · 20%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Respiratory muscle training versus sham training in ALS
Population: people with ALS
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Measures of lung capacity over the short term (less than 3 months) (change from baseline in % predicted FVC) Respiratory muscle training vs sham training | no estimate extracted | 1 study · 46 participants | Low |
Measures of lung capacity over the medium term (greater than 3 months but less than 1 year) (change from baseline in % predicted FVC) Respiratory muscle training vs sham training | no estimate extracted | 1 study · 24 participants | Low |
Measures of lung capacity over the long term (greater than 1 year) Respiratory muscle training vs sham training | no estimate extracted | NR | No studies |
Physical function in carrying out activities of daily living over the medium term (3 to 12 months; change from baseline) Respiratory muscle training vs sham training | no estimate extracted | 1 study · 24 participants | Low |
Quality of life (change from baseline) in the medium term Respiratory muscle training vs sham training | no estimate extracted | 1 study · 24 participants | Low |
Number of unscheduled hospitalisations for episodes of chest infection or acute exacerbation of chronic respiratory failure within 1 year of randomization Respiratory muscle training vs sham training | no estimate extracted | NR | No studies |
All adverse events Respiratory muscle training vs sham training | no estimate extracted | 2 studies · 38 participants | Very low Downgraded: risk of bias, imprecision |
Respiratory muscle training versus sham training in DMD
Population: children and young males with DMD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Measures of lung capacity over the short term (less than 3 months) Measured by: post‐intervention TLC Respiratory muscle training vs sham training | no estimate extracted | 1 study · 16 participants | Low Downgraded: imprecision |
Measures of lung capacity over the medium term (greater than 3 months but less than 1 year) Respiratory muscle training vs sham training | no estimate extracted | NR | No studies |
Measures of lung capacity over the long term (greater than 1 year) Respiratory muscle training vs sham training | no estimate extracted | NR | No studies |
Physical function in carrying out activities of daily living Respiratory muscle training vs sham training | no estimate extracted | NR | No studies |
Quality of life Respiratory muscle training vs sham training | no estimate extracted | NR | No studies |
Number of unscheduled hospitalizations for episodes of chest infection or acute exacerbation of chronic respiratory failure within 1 year of randomization Respiratory muscle training vs sham training | no estimate extracted | NR | No studies |
All adverse events Respiratory muscle training vs sham training | no estimate extracted | NR | No studies |
Respiratory muscle training versus no training in DMD
Population: children and young males with DMD
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Measures of lung capacity over the short term (less than 3 months) Respiratory muscle training vs no training | no estimate extracted | NR | No studies |
Measures of lung capacity over the medium term (greater than 3 months but less than 1 year) Measured by: post‐intervention % predicted VC Respiratory muscle training vs no training | no estimate extracted | 1 study · 30 participants | Low Downgraded: imprecision |
Measures of lung capacity over the long term (greater than 1 year) Respiratory muscle training vs no training | no estimate extracted | NR | No studies |
Physical function in carrying out activities of daily living Respiratory muscle training vs no training | no estimate extracted | NR | No studies |
Quality of life Respiratory muscle training vs no training | no estimate extracted | NR | No studies |
Number of unscheduled hospitalizations for episodes of chest infection or acute exacerbation of chronic respiratory failure within 1 year of randomization Respiratory muscle training vs no training | no estimate extracted | NR | No studies |
All adverse events Respiratory muscle training vs no training | no estimate extracted | NR | No studies |
Respiratory muscle training versus breathing exercises in limb‐girdle muscular dystrophy or Becker muscular dystrophy
Population: participants with limb‐girdle muscular dystrophy or Becker muscular dystrophy
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Measures of lung capacity over the short term (less than 3 months) Measured as change from baseline in FVC (L) Respiratory muscle training vs breathing exercises | no estimate extracted | 1 study · 21 participants | Very low Downgraded: risk of bias, imprecision |
Measures of lung capacity over the medium term (greater than 3 months but less than 1 year) Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |
Measures of lung capacity over the long term (greater than 1 year) Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |
Physical function in carrying out activities of daily living Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |
Quality of life Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |
Number of unscheduled hospitalisations for episodes of chest infection or acute exacerbation of chronic respiratory failure within 1 year of randomization Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |
All adverse events Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |
Respiratory muscle training versus breathing exercises in myasthenia gravis
Population: people with myasthenia gravis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Measures of lung capacity over the short term (less than 3 months) Measured by: post‐intervention TLC Respiratory muscle training vs breathing exercises | no estimate extracted | 1 study · 27 participants | Low Downgraded: risk of bias, imprecision |
Measures of lung capacity over the medium term (greater than 3 months but less than 1 year) Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |
Measures of lung capacity over the long term (greater than 1 year) Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |
Physical function in carrying out activities of daily living Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |
Quality of life Respiratory muscle training vs breathing exercises | no estimate extracted | 1 study · 27 participants | Very low Downgraded: risk of bias, imprecision |
Number of unscheduled hospitalizations for episodes of chest infection or acute exacerbation of chronic respiratory failure within 1 year of randomization Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |
All adverse events Respiratory muscle training vs breathing exercises | no estimate extracted | NR | No studies |