Findings

What do systematic reviews say?

900 questions · 932 findings · 149 reviews

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No studies found 215 · 23.1%GRADE not reported 65 · 7%Very low 234 · 25.1%Low 256 · 27.5%Moderate 134 · 14.4%High 28 · 3%

Viaskin milk patch vs placebo

Histological improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 9 participants
Low

Viaskin milk patch vs placebo

Endoscopic improvement (continuous) · active EoE pediatric patients

1 finding from 1 review

Medical treatment of eosinophilic esophagitis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Intervention not reported

Face‐to‐face behavioral intervention vs minimal or no support (Measured 3 to 6 months with CO‐validated prolonged and continuous abstinence, and self‐reported abstinence) · people who use waterpipe

The intervention may leads to higher face‐to‐face behavioral intervention vs minimal or no support… (low certainty).

1 finding from 1 review

Interventions for waterpipe smoking cessation 2023 · Cochrane Headline outcomes only
RR 2.64 [1.66, 4.2]
851 participants
Low

Intervention not reported

Bupropion therapy plus behavioral intervention vs behavioral intervention alone (continuous waterpipe smoking abstinence, defined as an expired CO of 9 ppm or less at the 6‐month postintervention · people who use waterpipe

It is very uncertain whether the intervention changes bupropion therapy plus behavioral intervention vs behavioral… (very low certainty).

1 finding from 1 review

Interventions for waterpipe smoking cessation 2023 · Cochrane Headline outcomes only
RR 0.77 [0.42, 1.41]
121 participants
Very low

Intervention not reported

Bupropion therapy plus behavioral support versus self‐help (continuous waterpipe smoking abstinence, defined as an expired CO of 9 ppm or less at the 6‐month postintervention · people who use waterpipe

It is very uncertain whether the intervention changes bupropion therapy plus behavioral support versus self‐help… (very low certainty).

1 finding from 1 review

Interventions for waterpipe smoking cessation 2023 · Cochrane Headline outcomes only
RR 1.94 [0.94, 4]
86 participants
Very low

Anti‐vascular endothelial growth factor (anti‐VEGF) with or without pan‐retinal photocoagulation (PRP) vs PRP alone

Regression of new vessels (continuous outcome): mean area of fluorescein leakage (mm2) fluorescein angiography · proliferative diabetic retinopathy

1 finding from 1 review

Anti‐vascular endothelial growth factor for proliferative diabetic retinopathy 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 189 participants
Low

Antidepressants vs placebo

Efficacy as a continuous outcome · adults with cancer and depression

1 finding from 1 review

Antidepressants for the treatment of depression in people with cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 511 participants
Very low

Selective serotonin reuptake inhibitors vs tricyclic antidepressants (TCAs)

Efficacy as a continuous outcome · patients with cancer and depression

1 finding from 1 review

Antidepressants for the treatment of depression in people with cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 237 participants
Very low

Mirtazapine vs tricyclic antidepressants (TCAs)

Efficacy as a continuous outcome · adults with cancer and depression

1 finding from 1 review

Antidepressants for the treatment of depression in people with cancer 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

Brief intervention vs brief advice, information, or assessment only

Harmful alcohol use · people with hazardous or harmful alcohol consumption

1 finding from 1 review

Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
no estimate extracted
17 studies · 3913 participants
Very low

Any Psychosocial intervention plus pharm vs psychosocial interventions

Harmful alcohol use · alcohol use disorder

1 finding from 1 review

Psychosocial and pharmacologic interventions to reduce harmful alcohol use in low‐ and middle‐income countries 2023 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 475 participants
Low

Weekly educational texts messages vs once every other week educational text messages

Flare‐ups or relapse (continuous) · people with inflammatory bowel disease

The review found no eligible studies for this question.

1 finding from 1 review

Patient education interventions for the management of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Patient education and standard care vs usual care

Flare‐ups or relapse (continuous) · people with inflammatory bowel disease

1 finding from 1 review

Patient education interventions for the management of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1022 participants
Moderate

Web‐based patient education vs other delivery of patient education

Flare‐ups or relapse (continuous) · people with inflammatory bowel disease

The review found no eligible studies for this question.

1 finding from 1 review

Patient education interventions for the management of inflammatory bowel disease 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Web‐based disease monitoring vs usual care

Flare‐ups or relapse (continuous) · people with inflammatory bowel disease

1 finding from 1 review

Remote care through telehealth for people with inflammatory bowel disease 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 909 participants
Moderate

Parenting interventions vs inactive control (usual care care, attention control, waitlist)

Parent‐child relationship or assessment of parenting · for parents who are experiencing CPTSD symptoms or have experienced maltreatment in their childhood

1 finding from 1 review

Interventions from pregnancy to two years after birth for parents experiencing complex post‐traumatic stress disorder… 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 153 participants
Low

Subgroup analyses: early vs standard initiation of kidney replacement therapy (KRT)

Kidney recovery functionby KRT: continuous KRT · AKI

Subgroup analyses: early showed no clear difference in kidney recovery functionby KRT: continuous KRT compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).

1 finding from 1 review

Timing of kidney replacement therapy initiation for acute kidney injury 2022 · Cochrane Headline outcomes only
RR 1.42 [0.99, 2.03]
6 studies · 583 participants
Moderate

Subgroup analyses: early vs standard initiation of kidney replacement therapy (KRT)

Kidney recovery functionby KRT: continuous and intermittent KRT · AKI

Subgroup analyses: early showed no clear difference in kidney recovery functionby KRT: continuous and intermittent KRT compared with standard initiation of kidney replacement therapy (KRT) (moderate certainty).

1 finding from 1 review

Timing of kidney replacement therapy initiation for acute kidney injury 2022 · Cochrane Headline outcomes only
RR 0.96 [0.91, 1.02]
4 studies · 4134 participants
Moderate

Systemic corticosteroids vs placebo

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · people with radicular low back pain (not due to spinal stenosis)

1 finding from 1 review

Systemic corticosteroids for radicular and non‐radicular low back pain 2022 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 430 participants
Moderate

Systemic corticosteroids vs placebo

Function (continuous) RDQ‐18 (scale 0–18) · people with non‐radicular low back pain

1 finding from 1 review

Systemic corticosteroids for radicular and non‐radicular low back pain 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Low