Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

441 questions · 461 findings · 48 reviews

No studies found 76 · 16.5%GRADE not reported 94 · 20.4%Very low 82 · 17.8%Low 119 · 25.8%Moderate 73 · 15.8%High 17 · 3.7%

Mineral trioxide aggregate (MTA) vs Calcium hydroxide + sodium hypochlorite (NaOCl)

Radiological failure · Children with extensive decay involving the dental pulp in primary teeth

Mineral trioxide aggregate (MTA) showed no clear difference in radiological failure compared with calcium hydroxide + sodium hypochlorite (NaOCl); GRADE not reported.

1 finding from 1 review

MegaGen EZ Plus blasted standard implants vs MegaGen EZ Plus calcium-incorporated (Xpeed) implants

Marginal bone level change · Adults with missing teeth who received osseointegrated root-formed oral implants, functionally loaded and followed for at least 1 year

MegaGen EZ Plus blasted standard implants showed no clear difference in marginal bone level change compared with megaGen EZ Plus calcium-incorporated (Xpeed) implants; GRADE not reported.

1 finding from 1 review

Calcitonin (salmon calcitonin nasal spray 200 IU/day) vs placebo

Increase in volume of more than 10% compared to the pretreatment measurement · Patients with histologically confirmed CGCG in one or both jaws and normal serum calcium and parathyroid hormone (PTH) levels

Calcitonin (salmon calcitonin nasal spray 200 IU/day) showed no clear difference in increase in volume of more than 10% compared to the pretreatment… compared with placebo; GRADE not reported.

1 finding from 1 review

Calcitonin (salmon calcitonin nasal spray 200 IU/day) vs placebo

Adverse events · Patients with histologically confirmed CGCG in one or both jaws and normal serum calcium and parathyroid hormone (PTH) levels
1 finding from 1 review
  • Adverse events were not described separately for each group. Trialists reported that adverse events were in most patients minimal and consisted of nausea, flushes and some dizziness. One patient had diarrhoea which…
    1 study · 14 participants
    GRADE not reported