Leaving the study early/ loss to · schizophrenia
Summary of findings table ‐ CBT without antipsychotics showed no clear difference in leaving the study early ‐ for any reason ‐ overall acceptability… compared with no specific treatment (low certainty).
1 finding from 1 review
Level of functioning · schizophrenia
1 finding from 1 review
Risk for at least one adverse event per patient · schizophrenia
1 finding from 1 review
Mental state · schizophrenia
1 finding from 1 review
Global state ‐ number of participants with relapse/exacerbations of psychosis (separated time points) ‐ < 12 months · schizophrenia
It is very uncertain whether summary of findings table ‐ CBT without antipsychotics changes global state ‐ number of participants with relapse/exacerbations of… compared with antipsychotics (very low certainty).
1 finding from 1 review
Leaving the study early/ loss to · schizophrenia
It is very uncertain whether summary of findings table ‐ CBT without antipsychotics changes leaving the study early ‐ for any reason ‐ overall acceptability… compared with antipsychotics (very low certainty).
1 finding from 1 review
Level of functioning · schizophrenia
1 finding from 1 review
Association between orthodontic treatment duration and ICLs incidence · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new ICLs
ICLs incidence increased with longer orthodontic treatment duration (meta-regression P<.01; ungraded).
1 finding from 1 review
Incidence of new ICLs (proportion of subjects developing new lesions) · Patients undergoing fixed orthodontic treatment with fixed (multibracket) appliances, followed for development of new ICLs
About 48% of patients developed new ICLs during fixed orthodontic treatment (pooled incidence 0.48, 95% CI 0.33-0.63; very low certainty; very high heterogeneity).
1 finding from 1 review
Prevalence of ICLs (proportion of tooth surfaces affected) · Patients (permanent dentition) during or after fixed orthodontic treatment with fixed (multibracket) appliances
About 22% of tooth surfaces showed ICLs during/after fixed orthodontic treatment (pooled 0.22, 95% CI 0.14-0.33; very low certainty; extreme heterogeneity).
1 finding from 1 review
Prevalence of ICLs (proportion of subjects affected) · Patients (permanent dentition) during or after fixed orthodontic treatment with fixed (multibracket) appliances
Around 57% of patients had ICLs during or after fixed orthodontic treatment (pooled prevalence 0.57, 95% CI 0.48-0.65; very low certainty; very high heterogeneity).
1 finding from 1 review
50% or greater reduction in seizure frequency · people with drug‐resistant focal epilepsy
Summary of findings: lamotrigine probably leads to higher 50% or greater reduction in seizure frequency (ITT analysis) compared with placebo (moderate certainty).
1 finding from 1 review
Treatment withdrawal · people with drug‐resistant focal epilepsy
Summary of findings: lamotrigine showed no clear difference in treatment withdrawal compared with placebo (moderate certainty).
1 finding from 1 review
Ataxia · people with drug‐resistant focal epilepsy
Summary of findings: lamotrigine probably leads to higher ataxia compared with placebo (moderate certainty).
1 finding from 1 review
Dizziness · people with drug‐resistant focal epilepsy
Summary of findings: lamotrigine probably leads to higher dizziness compared with placebo (moderate certainty).
1 finding from 1 review
Fatigue · people with drug‐resistant focal epilepsy
Summary of findings: lamotrigine probably leads to lower fatigue compared with placebo (moderate certainty).
1 finding from 1 review
Nausea · people with drug‐resistant focal epilepsy
Summary of findings: lamotrigine probably leads to higher nausea compared with placebo (moderate certainty).
1 finding from 1 review
Diplopia · people with drug‐resistant focal epilepsy
Summary of findings: lamotrigine probably leads to higher diplopia compared with placebo (moderate certainty).
1 finding from 1 review
FEV1 (% predicted): mean change from baseline · adults and children with cystic fibrosis
1 finding from 1 review
FEF25–75: rate of decline in FEF25–75 · adults and children with cystic fibrosis
1 finding from 1 review