What do systematic reviews say?

Summary of findings table ‐ Ibuprofen 800 mg vs prophylactic ibuprofen 800 mg women having medical abortion before 14 weeks? gestation

Summary of findings table ‐ Therapeutic ibuprofen 800 mg showed no clear difference in complete abortion rate compared with prophylactic ibuprofen 800 mg women having medical abortion before… (low certainty).

• Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
  OR 1.42 [0.31, 6.5]
  1 study · 228 participants
  Low

Summary of findings table ‐ Ibuprofen 800 mg vs prophylactic ibuprofen 800 mg women having medical abortion before 14 weeks? gestation

The review found no eligible studies for this question.

• Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Ibuprofen 800 mg vs prophylactic ibuprofen 800 mg women having medical abortion before 14 weeks? gestation

Summary of findings table ‐ Therapeutic ibuprofen 800 mg showed no clear difference in unscheduled contact with care compared with prophylactic ibuprofen 800 mg women having medical abortion before… (low certainty).

• Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
  OR 1.03 [0.6, 1.77]
  1 study · 228 participants
  Low

Summary of findings table ‐ Ibuprofen 800 mg vs prophylactic ibuprofen 800 mg women having medical abortion before 14 weeks? gestation

The review found no eligible studies for this question.

• Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Ibuprofen 800 mg vs prophylactic ibuprofen 800 mg women having medical abortion before 14 weeks? gestation

Summary of findings table ‐ Therapeutic ibuprofen 800 mg showed no clear difference in patient satisfaction with abortion care overall compared with prophylactic ibuprofen 800 mg women having medical abortion before… (low certainty).

• Pain management for medical abortion before 14 weeks’ gestation 2022 · Cochrane Headline outcomes only
  OR 0.52 [0.09, 2.89]
  1 study · 228 participants
  Low

Summary of findings table ‐ Teaching Recovery Techniques vs waiting list control

• Community‐based interventions for improving mental health in refugee children and adolescents in high‐income countries 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 63 participants
  Low

Summary of findings table ‐ Teaching Recovery Techniques vs waiting list control

• Community‐based interventions for improving mental health in refugee children and adolescents in high‐income countries 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 63 participants
  Low

Summary of findings table ‐ Teaching Recovery Techniques vs waiting list control

• Community‐based interventions for improving mental health in refugee children and adolescents in high‐income countries 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 16 participants
  Very low

Summary of findings table ‐ Teaching Recovery Techniques vs waiting list control

• Community‐based interventions for improving mental health in refugee children and adolescents in high‐income countries 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 16 participants
  Very low

Summary of findings table ‐ Teaching Recovery Techniques vs waiting list control

• Community‐based interventions for improving mental health in refugee children and adolescents in high‐income countries 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  Very low
• Community‐based interventions for improving mental health in refugee children and adolescents in high‐income countries 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 82 participants
  Low

Summary of findings table ‐ Teaching Recovery Techniques vs waiting list control

• Community‐based interventions for improving mental health in refugee children and adolescents in high‐income countries 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 31 participants
  Very low
• Community‐based interventions for improving mental health in refugee children and adolescents in high‐income countries 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 82 participants
  Low

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

• Antipsychotic dose reduction compared to dose continuation for people with schizophrenia 2022 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 719 participants
  Moderate

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

It is very uncertain whether summary of findings table ‐ Antipsychotic dose reduction changes service use ‐ readmission to hospital (combined time points) compared with dose continuation (very low certainty).

• Antipsychotic dose reduction compared to dose continuation for people with schizophrenia 2022 · Cochrane Headline outcomes only
  RR 1.53 [0.84, 2.81]
  9 studies · 1433 participants
  Very low

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

Summary of findings table ‐ Antipsychotic dose reduction probably leads to higher adverse effect ‐ leaving the study early due to adverse effects ‐… compared with dose continuation (moderate certainty).

• Antipsychotic dose reduction compared to dose continuation for people with schizophrenia 2022 · Cochrane Headline outcomes only
  RR 2.2 [1.39, 3.49]
  10 studies · 1340 participants
  Moderate

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

• Antipsychotic dose reduction compared to dose continuation for people with schizophrenia 2022 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 966 participants
  High

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

Summary of findings table ‐ Antipsychotic dose reduction may leads to higher global state ‐ number of participants with relapse/exacerbations of… compared with dose continuation (low certainty).

• Antipsychotic dose reduction compared to dose continuation for people with schizophrenia 2022 · Cochrane Headline outcomes only
  RR 2.16 [1.52, 3.06]
  20 studies · 2481 participants
  Low

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

Summary of findings table ‐ Antipsychotic dose reduction probably leads to higher leaving the study early ‐ for any reason ‐ overall acceptability… compared with dose continuation (moderate certainty).

• Antipsychotic dose reduction compared to dose continuation for people with schizophrenia 2022 · Cochrane Headline outcomes only
  RR 1.38 [1.05, 1.81]
  12 studies · 1551 participants
  Moderate

Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation

Summary of findings table ‐ Antipsychotic dose reduction showed no clear difference in adverse effects ‐ number of participants with at least 1 adverse… compared with dose continuation (moderate certainty).

• Antipsychotic dose reduction compared to dose continuation for people with schizophrenia 2022 · Cochrane Headline outcomes only
  RR 1.03 [0.94, 1.12]
  5 studies · 998 participants
  Moderate

Summary of findings ‐ Inhaled mannitol plus dornase alfa vs dornase alfa

• Inhaled mannitol for cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  231 participants
  Very low

Summary of findings ‐ Inhaled mannitol plus dornase alfa vs dornase alfa

It is very uncertain whether summary of findings ‐ Inhaled mannitol plus dornase alfa changes lung function: FEV1mL (percentage change from baseline) compared with dornase alfa (very low certainty).

• Inhaled mannitol for cystic fibrosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  231 participants
  Very low