Question · asked by 1 review
Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation: Leaving the study early ‐ for any reason ‐ overall acceptability (combined time points)
- Population
- patients with schizophrenia
- Intervention
- Summary of findings table ‐ Antipsychotic dose reduction
- Comparison
- dose continuation
- Outcome
- Leaving the study early ‐ for any reason ‐ overall acceptability (combined time points)
Summary of findings table ‐ Antipsychotic dose reduction probably leads to higher leaving the study early ‐ for any reason ‐ overall acceptability… compared with dose continuation (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Summary of findings table ‐ Antipsychotic dose reduction vs dose continuation Leaving the study early ‐ for any reason ‐ overall acceptability (combined time points) · people with schizophrenia Summary of findings table ‐ Antipsychotic dose reduction probably leads to higher leaving the study early ‐ for any reason ‐ overall acceptability… compared with dose continuation (moderate certainty). Antipsychotic dose reduction compared to dose continuation for people with schizophrenia (2022) · Cochrane Headline outcomes only | RR 1.38 [1.05, 1.81] | 12 studies · 1551 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Antipsychotic dose reduction compared to dose continuation for people with schizophrenia 2022 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.