Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,126 questions · 1,225 findings · 111 reviews

No studies found 235 · 19.2%GRADE not reported 260 · 21.2%Very low 207 · 16.9%Low 271 · 22.1%Moderate 177 · 14.4%High 75 · 6.1%

Vitamin D plus calcium vs placebo or control

Hip Fracture · post‐menopausal women and older people at risk of osteoporotic fractures

Vitamin D [D2, D3 or 25(OH)D] plus calcium leads to lower persons sustaining new hip fracture (1 year estimate) compared with control or placebo (high certainty).

1 finding from 1 review

Vitamin D plus calcium vs placebo or control

New fractures · post‐menopausal women and older people at risk of osteoporotic fractures

Vitamin D [D2, D3 or 25(OH)D] plus calcium leads to lower persons sustaining any new fracture (1 year estimate) compared with control or placebo (high certainty).

1 finding from 1 review

Vitamin D plus calcium vs placebo

Adverse events: serum calcium above normal · relatively healthy postmenopausal women

Vitamin D plus calcium showed no clear difference in adverse events: serum calcium above normal compared with placebo (low certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants achieving 'response' by PGA · scalp psoriasis

Steroid plus vitamin D leads to higher number of participants achieving 'response' by PGA compared with steroid (high certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants achieving 'clearance' by IGA · scalp psoriasis

Steroid plus vitamin D probably leads to higher number of participants achieving 'clearance' by IGA compared with steroid (moderate certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants achieving 'response' by IGA · scalp psoriasis

Steroid plus vitamin D probably leads to higher number of participants achieving 'response' by IGA compared with steroid (moderate certainty).

1 finding from 1 review

Steroid plus vitamin D vs steroids

Number of participants withdrawing due to adverse events (AE) · scalp psoriasis

Steroid plus vitamin D showed no clear difference in number of participants withdrawing due to adverse events (AE) compared with steroid (moderate certainty).

1 finding from 1 review