Cochrane · systematic review · CD009687
Topical treatments for scalp psoriasis
Schlager, JG, Rosumeck, S, Werner, RN, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
SkinAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
15
current version
GRADE rated
12
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 3 · 20%Very low 0 · 0%Low 0 · 0%Moderate 8 · 53.3%High 4 · 26.7%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Steroid compared to vitamin D for scalp psoriasis
Population: scalp psoriasis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of participants achieving 'clearance' by IGA Steroid vs vitamin D | RR 1.82 [1.52, 2.18] | 4 studies · 2180 participants | Moderate Downgraded: risk of bias |
Number of participants achieving 'response' by IGA Steroid vs vitamin D | RR 2.09 [1.8, 2.41] | 3 studies · 1827 participants | High |
Quality of life Steroid vs vitamin D | no estimate extracted | 0 studies · 0 participants | Ungraded |
Number of participants withdrawing due to adverse events (AE) Steroid vs vitamin D | RR 0.22 [0.11, 0.42] | 4 studies · 2291 participants | Moderate Downgraded: risk of bias, imprecision |
Number of participants achieving 'response' by PGA Steroid vs vitamin D | RR 1.48 [1.28, 1.72] | 3 studies · 1827 participants | Moderate Downgraded: risk of bias, imprecision |
Steroid plus vitamin D compared to steroid for scalp psoriasis
Population: scalp psoriasis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of participants achieving 'clearance' by IGA Steroid plus vitamin D vs steroid | RR 1.22 [1.08, 1.36] | 4 studies · 2474 participants | Moderate Downgraded: imprecision |
Number of participants achieving 'response' by IGA Steroid plus vitamin D vs steroid | RR 1.15 [1.06, 1.25] | 3 studies · 2444 participants | Moderate Downgraded: imprecision, inconsistency |
Quality of life Steroid plus vitamin D vs steroid | no estimate extracted | 0 studies · 0 participants | Ungraded |
Number of participants withdrawing due to adverse events (AE) Steroid plus vitamin D vs steroid | RR 0.88 [0.42, 1.88] | 3 studies · 2433 participants | Moderate Downgraded: imprecision, inconsistency |
Number of participants achieving 'response' by PGA Steroid plus vitamin D vs steroid | RR 1.13 [1.06, 1.2] | 2 studies · 2226 participants | High |
Steroid plus vitamin D compared to vitamin D for scalp psoriasis
Population: scalp psoriasis
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Number of participants achieving 'clearance' by IGA Steroid plus vitamin D vs vitamin D | RR 2.28 [1.87, 2.78] | 4 studies · 2008 participants | High |
Number of participants achieving 'response' by IGA Steroid plus vitamin D vs vitamin D | RR 2.31 [1.75, 3.04] | 4 studies · 2222 participants | Moderate Downgraded: inconsistency |
Quality of life Steroid plus vitamin D vs vitamin D | no estimate extracted | 0 studies · 0 participants | Ungraded |
Number of participants withdrawing due to adverse events Steroid plus vitamin D vs vitamin D | RR 0.19 [0.11, 0.36] | 3 studies · 1970 participants | High |
Number of participants achieving 'response' by PGA Steroid plus vitamin D vs vitamin D | RR 1.76 [1.46, 2.12] | 4 studies · 2222 participants | Moderate Downgraded: inconsistency |