Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,315 questions · 23,557 findings · 2,311 reviews

No studies found 4,183 · 17.8%GRADE not reported 3,930 · 16.7%Very low 5,371 · 22.8%Low 5,787 · 24.6%Moderate 3,320 · 14.1%High 966 · 4.1%

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Exposure vs no exposure to the smell and taste of milk with tube feeds

Late infection during hospitalisation (bacterial or fungal infection confirmed by presence of blood or CSF infection, with initiation of symptoms > 48 hours after birth) · preterm infants

Exposure showed no clear difference in late infection during hospitalisation (bacterial or fungal infection… compared with no exposure to the smell and taste of milk with tube feeds (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Vitamin B12 supplementation vs no supplementation or placebo

Preterm birth · pregnant women

Summary of findings table ‐ Vitamin B12 supplementation showed no clear difference in preterm birth (< 37 weeks) compared with placebo/no vitamin B12 supplementation (low certainty).

1 finding from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Caries presence in primary teeth · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age

It is very uncertain whether prophylaxis (teeth cleaning) and CHX or iodine-NaF solution… changes caries presence in primary teeth compared with placebo (very low certainty).

1 finding from 1 review

Prophylaxis (teeth cleaning) and CHX or iodine-NaF solution application in the dentition of women (mothers) vs placebo

Child microbiological presence (mutans streptococci acquisition) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
1 finding from 1 review

Dietary advice on how to achieve a healthy diet for infants (tailored advice focused on a diet low in saturated fat and cholesterol intake) vs usual care

Caries presence in primary teeth · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…

It is very uncertain whether dietary advice on how to achieve a healthy diet for infants… changes caries presence in primary teeth compared with standard care (very low certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Multiple pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in multiple Pregnancy compared with c‐IVF (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Ectopic pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in ectopic Pregnancy compared with c‐IVF (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Prematurity · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in prematurity compared with c‐IVF (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Clinical pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in clinical Pregnancy compared with c‐IVF (low certainty).

1 finding from 1 review

Summary of findings table ‐ ICSI vs c‐IVF

Viable intrauterine Pregnancy · : Couples with males presenting normal total sperm count and motility were included in this review.

Summary of findings table ‐ ICSI showed no clear difference in viable intrauterine Pregnancy compared with c‐IVF (moderate certainty).

1 finding from 1 review

Pharmacological interventions vs placebo

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether pharmacological interventions changes depression: meeting study criteria for depression at end of… compared with placebo (very low certainty).

2 findings from 1 review

Non‐invasive brain stimulation vs usual care with or without sham interventions

Depression: meeting study criteria for depression at end of · people with depression after stroke
2 findings from 1 review

Psychological therapy vs usual care or attention control

Depression: meeting study criteria for depression at end of · people with depression after stroke

It is very uncertain whether psychological therapy changes depression: meeting study criteria for depression at end of… compared with usual care and/or attention control (very low certainty).

2 findings from 1 review