Mean change in maximum K from baseline or final value—at 12 months or more (diopters) · participants with progressive keratoconus
1 finding from 1 review
Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with chronic obstructive pulmonary disease
Supervised maintenance programme following pulmonary rehabilitation showed no clear difference in exacerbation: number of people experiencing one or more exacerbation compared with usual care (low certainty).
1 finding from 1 review
Number of people with one or more isolates of S aureus (sensitive strains) · children with cystic fibrosis
Summary of findings ‐ Prophylactic may leads to lower number of people with one or more isolates of S aureus (sensitive… compared with 'as required' anti‐staphylococcal antibiotics (low certainty).
1 finding from 1 review
Number of people with one or more isolates of P aeruginosa · children with cystic fibrosis
Summary of findings ‐ Prophylactic showed no clear difference in number of people with one or more isolates of P aeruginosa compared with 'as required' anti‐staphylococcal antibiotics (low certainty).
1 finding from 1 review
Exacerbations (number of people experiencing ≥ 1 exacerbations) · patients with stable chronic obstructive pulmonary disease
Phosphodiesterase‐4 inhibitors leads to lower number of participants with 1 or more exacerbations compared with placebo (high certainty).
1 finding from 1 review
Progression to visual loss (loss of 3 or more lines on logMAR chart) · people with neovascular AMD
Radiotherapy showed no clear difference in loss of 3 or more lines of best‐corrected visual acuity Measured… compared with control (low certainty).
1 finding from 1 review
RR 0.82 [0.64, 1.04]
Studies not reported
Low
Progression to visual loss (loss of 3 or more lines on logMAR chart) · people with neovascular AMD
Radiotherapy combined with anti‐VEGF probably leads to higher loss of 3 or more lines of best‐corrected visual acuity Measured… compared with anti‐VEGF alone (moderate certainty).
1 finding from 1 review
RR 2.11 [1.4, 3.17]
Studies not reported
Moderate
Intervention not reported
Use of 1 or more red blood cell transfusions (low and high doses of EPO) · preterm infants with low birth weight
The intervention may leads to lower use of 1 or more red blood cell transfusions (low and high doses of… (low certainty).
1 finding from 1 review
Intervention not reported
Use of one or more red blood cell transfusions (low and high dose of EPO) during initial hospital stay · preterm infants with low birth weight
It is very uncertain whether the intervention changes use of one or more red blood cell transfusions (low and high dose of… (very low certainty).
1 finding from 1 review
Gain 3+ lines of visual acuity at 1 year · macular edema in diabetes
Intravitreal fluocinolone acetonide implant 0.19 mg probably leads to higher gain of three or more lines visual acuity ‐ 12 months compared with sham (moderate certainty).
1 finding from 1 review
Gain 3+ lines of visual acuity at 1 year · macular edema in diabetes
Intravitreal dexamethasone implant 0.7 mg showed no clear difference in gain of three or more lines visual acuity ‐ 12 months compared with sham (moderate certainty).
1 finding from 1 review
Gain of 3 or more lines of visual acuity · macular edema in diabetes
It is very uncertain whether intravitreal triamcinolone acetonide injection 4 mg changes gain of three or more lines visual acuity ‐ 24 months** compared with sham (very low certainty).
1 finding from 1 review
RR 4.12 [0.48, 34.99]
Studies not reported
Very low
Gain 3+ lines of visual acuity at 1 year · macular edema in diabetes
Intravitreal triamcinolone acetonide injection 4 mg showed no clear difference in gain of three or more lines visual acuity ‐ 12 months compared with macular laser (low certainty).
1 finding from 1 review
RR 0.85 [0.55, 1.3]
Studies not reported
Low
Gain of 3 or more lines of visual acuity · macular edema in diabetes
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Gain 3+ lines of visual acuity at 1 year · macular edema in diabetes
Intravitreal dexamethasone implant 0.7 mg may leads to lower gain of three or more lines visual acuity ‐ 12 months compared with intravitreal antiVEGF (low certainty).
1 finding from 1 review
RR 0.99
Studies not reported
Low
Number of people incurring one or more complications requiring substantive treatment · adults with dorsally displaced distal radius fractures
1 finding from 1 review
Overall number of people incurring one or more complications · adults with dorsally displaced distal radius fractures
1 finding from 1 review
Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome
It is very uncertain whether brain‐derived neurotrophic factor changes participants with 1 or more serious adverse events compared with placebo (very low certainty).
1 finding from 1 review
Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome
It is very uncertain whether cerebrospinal fluid filtration changes participants with 1 or more serious adverse events compared with plasma exchange (very low certainty).
1 finding from 1 review
Participants with 1 or more serious adverse events · patients with Guillain‐Barré syndrome
1 finding from 1 review