Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

313 questions · 352 findings · 23 reviews · Drugs and Alcohol

No studies found 16 · 4.5%GRADE not reported 34 · 9.7%Very low 113 · 32.1%Low 117 · 33.2%Moderate 57 · 16.2%High 15 · 4.3%

Intervention not reported

Point‐prevalence abstinence rates at short‐term · adults with cannabis use disorder or frequent cannabis use

The intervention may leads to higher point‐prevalence abstinence rates at short‐term (low certainty).

1 finding from 1 review

Intervention not reported

Cannabis use quantity per day at short‐term · adults with cannabis use disorder or frequent cannabis use

It is very uncertain whether the intervention changes cannabis use quantity per day at short‐term (very low certainty).

1 finding from 1 review

Intervention not reported

Symptoms of dependence at short‐term · adults with cannabis use disorder or frequent cannabis use

The intervention may leads to higher symptoms of dependence at short‐term (low certainty).

1 finding from 1 review

Intervention not reported

Cannabis‐related problems at short‐term · adults with cannabis use disorder or frequent cannabis use

The intervention may leads to higher cannabis‐related problems at short‐term (low certainty).

1 finding from 1 review

Intervention not reported

Retention in treatment · adults with cannabis use disorder or frequent cannabis use
1 finding from 1 review

CBT (plus taper) vs taper

Successful discontinuation of BZDs‐ post treatment Objective and subjective · patients with BZD harmful use, abuse or dependence

CBT (plus taper) probably leads to higher successful discontinuation of BZDs‐ post treatment Objective and… compared with taper (moderate certainty).

1 finding from 1 review

MI vs TAU

Successful discontinuation of BZDs‐ post treatment Objective and subjective · patients with BZD harmful use, abuse or dependence

It is very uncertain whether MI changes successful discontinuation of BZDs‐ post treatment Objective and… compared with TAU (very low certainty).

2 findings from 1 review

naltrexone vs no pharmacological

Criminal activity dichotomous ‐ Reincarceration official records · patients with drug‐using offenders

Summary of findings for the main comparisons: Antagonost (Naltrexone) probably leads to lower criminal activity dichotomous ‐ Reincarceration official records compared with no pharmacological (moderate certainty).

1 finding from 1 review