Cochrane · systematic review · CD009652
Psychosocial interventions for benzodiazepine harmful use, abuse or dependence
Darker, CD, Sweeney, BP, Barry, JM, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library
Drugs and AlcoholAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 33.3%Low 2 · 33.3%Moderate 2 · 33.3%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
CBT (plus taper) versus taper for BZD harmful use, abuse or dependence
Population: patients with BZD harmful use, abuse or dependence
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Successful discontinuation of BZDs‐ post treatment Objective and subjective CBT (plus taper) vs taper | RR 1.4 [1.05, 1.86] | 9 studies · 423 participants | Moderate Downgraded: risk of bias, imprecision |
Successful discontinuation of BZDs‐ 12 month CBT (plus taper) vs taper | RR 1.42 [0.89, 2.28] | 5 studies · 284 participants | Moderate Downgraded: risk of bias, imprecision |
Reduce BZDs> 50% ‐ post treatment Objective CBT (plus taper) vs taper | OR 0.93 [0.11, 8.18] | 3 studies · 178 participants | Low Downgraded: risk of bias, imprecision |
Reduce BZDs> 50% ‐ 12 month CBT (plus taper) vs taper | OR 1.07 [0.14, 8.21] | 2 studies · 125 participants | Low Downgraded: risk of bias, imprecision |
MI versus TAU for BZD harmful use, abuse or dependence
Population: patients with BZD harmful use, abuse or dependence
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Successful discontinuation of BZDs‐ post treatment Objective and subjective MI vs TAU | RR 4.43 [0.16, 125.35] | 2 studies · 34 participants | Very low Downgraded: risk of bias, imprecision |
Successful discontinuation of BZDs‐ 3 month MI vs TAU | RR 3.46 [0.53, 22.45] | 4 studies · 80 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |