It is very uncertain whether barbiturate treatment changes cerebral palsy compared with placebo or no treatment (very low certainty).
It is very uncertain whether barbiturate treatment changes developmental delay compared with placebo or no treatment (very low certainty).
Barbiturate treatment may leads to lower seizures (clinical or electrographic) compared with placebo or no treatment (low certainty).
Barbiturate treatment showed no clear difference in abnormal neurologic exam at discharge compared with placebo or no treatment (low certainty).
Antithrombin showed no clear difference in intraventricular hemorrhage (any severity, grade 1 to 4) compared with placebo (low certainty).
Antithrombin showed no clear difference in severe Intraventricular hemorrhage (grade 3 to 4) compared with placebo (low certainty).
It is very uncertain whether antithrombin changes neonatal mortality (all‐cause, < 28 days of age) compared with placebo (very low certainty).
It is very uncertain whether heparin changes any Intraventricular Haemorrage (IVH) compared with placebo/no treatment (very low certainty).
Heparin showed no clear difference in severe IVH compared with placebo/no treatment (low certainty).
Heparin showed no clear difference in neonatal mortality (all‐cause) compared with placebo/no treatment (low certainty).
It is very uncertain whether epinephrine changes need for mechanical ventilation (yes/no) compared with placebo, no treatment or any other drugs (very low certainty).
It is very uncertain whether adjunctive steroid changes all‐cause death until hospital discharge compared with placebo (very low certainty).
Adjunctive steroid showed no clear difference in number of participants with developmental delay compared with placebo (low certainty).
Adjunctive steroid showed no clear difference in hearing loss at 2 years of age compared with placebo (low certainty).