Cochrane · systematic review · CD011718
Heparin for the prevention of intraventricular haemorrhage in preterm infants
Bruschettini, M, Romantsik, O, Zappettini, S, et al. · Cochrane Database of Systematic Reviews · 2016 · Cochrane Library
NeonatalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
3
current version
GRADE rated
3
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 33.3%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Heparin compared to placebo/no treatment for the prevention of intraventricular haemorrhage in preterm infants
Population: preterm infants at risk of intraventricular haemorrhage
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Any Intraventricular Haemorrage (IVH) Heparin vs placebo/no treatment | RR 0.93 [0.61, 1.41] | 2 studies · 155 participants | Very low Downgraded: risk of bias, imprecision, inconsistency |
Severe IVH Heparin vs placebo/no treatment | RR 1.01 [0.46, 2.23] | 2 studies · 155 participants | Low Downgraded: risk of bias, imprecision, inconsistency |
Neonatal mortality (all‐cause) Heparin vs placebo/no treatment | RR 0.69 [0.28, 1.67] | 2 studies · 155 participants | Low Downgraded: risk of bias, imprecision, inconsistency |