Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

332 questions · 335 findings · 55 reviews · Headline outcomes only

No studies found 77 · 23%GRADE not reported 3 · 0.9%Very low 113 · 33.7%Low 75 · 22.4%Moderate 61 · 18.2%High 6 · 1.8%

Endoscopy vs surgery

Relief of pain · participants with painful obstructive chronic pancreatitis

Endoscopy probably leads to higher pain relief ‐ middle‐term compared with surgery (moderate certainty).

2 findings from 1 review

Cyanoacrylate vs band ligation

Mortality Total of deaths and the end of · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes mortality Total of deaths and the end of compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Re‐bleeding Bleeding after initial success in the intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes re‐bleeding Bleeding after initial success in the intervention compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes control of bleeding Success in control the active variceal bleeding compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review