Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,018 questions · 3,100 findings · 369 reviews · Headline outcomes only

No studies found 774 · 25%GRADE not reported 108 · 3.5%Very low 727 · 23.5%Low 840 · 27.1%Moderate 474 · 15.3%High 177 · 5.7%

Intervention not reported

Participants with at least 30% or at least 50% reduction in pain · people with cancer pain
1 finding from 1 review

Intervention not reported

PGIC much or very much improved · people with cancer pain
1 finding from 1 review

Intervention not reported

Mean pain intensity at end of study · people with cancer pain
1 finding from 1 review

Intervention not reported

Pain no worse than mild at one or two weeks (or equivalent) · people with cancer pain
1 finding from 1 review

Intervention not reported

Mean quality of life or "well‐being" · people with cancer pain
1 finding from 1 review

Intervention not reported

Participant preference · people with cancer pain
1 finding from 1 review

Intervention not reported

Serious adverse events · people with cancer pain
1 finding from 1 review

5‐ASA vs placebo

Relapse, drop‐outs classed as relapse, grouped by length of · patients with maintenance of medically‐induced remission in Crohn's disease

5‐ASA showed no clear difference in relapse, drop‐outs classed as relapse, grouped by length of compared with placebo (moderate certainty).

3 findings from 1 review

Intervention not reported

Number of participants receiving transfusion with allogeneic blood: aprotinin vs placebo · children undergoing surgery for scoliosis

It is very uncertain whether the intervention changes number of participants receiving transfusion with allogeneic blood:… (very low certainty).

1 finding from 1 review