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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Promotion of female and male condom vs promotion of male condom
Chlamydia incidence among FSWs at 3‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.71 [0.52, 0.98]1 study · 504 participantsHigh
Promotion of female and male condom vs promotion of male condom
Gonorrhoea incidence among FSWs at 3‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.63 [0.45, 0.88]1 study · 504 participantsHigh
Promotion of female and male condom vs promotion of male condom
Consistent male condom use at 3‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.88 [0.83, 0.92]2 studies · 572 participantsHigh
Promotion of female and male condom vs promotion of male condom
Consistent female condom use by FSWs at 3‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.12 [0.09, 0.17]2 studies · 564 participantsHigh
Promotion of female and male condom vs promotion of male condom
Consistent female condom use by FSWs at 24‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.15 [0.09, 0.28]1 study · 128 participantsHigh
Social cognitive theory vs standard counseling
Syphilis incidence among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.46 [0.18, 1.19]1 study · 709 participantsModerate
Promotion of female and male condom vs promotion of male condom
Consistent male condom use at 24‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.91 [0.82, 1.02]1 study · 128 participantsModerate
VCT vs standard care of STI
Syphilis prevalence among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.52 [0.23, 1.18]1 study · 278 participantsVery low
VCT vs standard care of STI
Gonorrhoea prevalence among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.83 [0.4, 1.74]1 study · 278 participantsVery low
VCT vs standard care of STI
Chlamydia prevalence among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.67 [0.4, 1.13]1 study · 278 participantsVery low
VCT vs standard care of STI
Trichomonas prevalence among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.52 [0.23, 1.18]1 study · 278 participantsVery low
VCT vs standard care of STI
Genital warts prevalence among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.22 [0.05, 0.98]1 study · 278 participantsLow
VCT vs standard care of STI
Consistent condom use by FSWs with clients at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 2.05 [1.48, 2.85]1 study · 278 participantsVery low
VCT vs standard care of STI
HIV/STI knowledge among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 1.28 [0.81, 2.04]1 study · 278 participantsVery low
Social cognitive theory vs standard counseling
Gonorrhoea incidence among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.69 [0.3, 1.58]1 study · 709 participantsModerate
Social cognitive theory vs standard counseling
Any STIs incidence among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.57 [0.34, 0.96]1 study · 709 participantsModerate
Social cognitive theory vs standard counseling
Consistent condom use by FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 1.14 [1.07, 1.21]2 studies · 804 participantsVery low
Social cognitive theory vs standard counseling
Drug use among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.65 [0.36, 1.16]2 studies · 772 participantsLow
Social cognitive theory vs standard counseling
Alcohol use among FSWs at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.68 [0.46, 1]2 studies · 772 participantsLow
Social cognitive theory for promotion of condom use vs no intervention
Consistent condom use by FSWs with clients at 6‐month · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.89 [0.61, 1.3]1 study · 98 participantsModerate
Social cognitive theory for promotion of condom use vs no intervention
Consistent condom use by FSWs with clients in the past 7‐day · sex workers
Behavioral interventions to reduce the transmission of HIV infection among sex workers and their clients in… (2012) · Cochrane
RR 0.92 [0.68, 1.24]1 study · 98 participantsModerate
Intervention NR
Need for second recompression Simple count · patients with decompression illness
Recompression and adjunctive therapy for decompression illness (2012) · Cochrane
RR 0.64 [0.46, 0.86]1 study · 180 participantsHigh
SERMS vs no treatment
Percent change from baseline in leiomyoma size · patients with uterine leiomyomas
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas (2012) · Cochrane
no estimate extracted1 study · 23 participantsVery low
SERMS (raloxifene 60mg) vs placebo
Size (cm3) of leiomyoma · patients with uterine leiomyomas
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas (2012) · Cochrane
no estimate extracted1 study · 58 participantsLow
SERMS (raloxifene 60mg) vs placebo
Size (cm3) of leiomyoma · patients with uterine leiomyomas
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas (2012) · Cochrane
no estimate extracted1 study · 58 participantsLow
SERMS (raloxifene 60mg) vs placebo
Percent change from baseline in leiomyoma size in GHRH‐analogue treated women · patients with uterine leiomyomas
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas (2012) · Cochrane
no estimate extracted1 study · 91 participantsLow
SERMS (raloxifene 180 mg) vs placebo
Size (cm3) of leiomyoma · patients with uterine leiomyomas
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas (2012) · Cochrane
no estimate extracted1 study · 60 participantsLow
SERMS (raloxifene 180 mg) vs placebo
Size (cm3) of leiomyoma · patients with uterine leiomyomas
Selective estrogen receptor modulators (SERMs) for uterine leiomyomas (2012) · Cochrane
no estimate extracted1 study · 59 participantsLow
Human deoxyribonuclease vs placebo
Clinical failure Number of children with no significant improvement in cough diary scores at two weeks (average of day 13 to 14) · children with primary (intrinsic) tracheomalacia
Interventions for primary (intrinsic) tracheomalacia in children (2012) · Cochrane
OR 1.38 [0.37, 5.14]1 study · 38 participantsLow
Human deoxyribonuclease vs placebo
Daytime cough diary scores (change from baseline) · children with primary (intrinsic) tracheomalacia
Interventions for primary (intrinsic) tracheomalacia in children (2012) · Cochrane
no estimate extracted1 study · 38 participantsLow
Human deoxyribonuclease vs placebo
Night time cough diary score (change from baseline) · children with primary (intrinsic) tracheomalacia
Interventions for primary (intrinsic) tracheomalacia in children (2012) · Cochrane
no estimate extracted1 study · 38 participantsLow
Human deoxyribonuclease vs placebo
Night time VAS (change from baseline) · children with primary (intrinsic) tracheomalacia
Interventions for primary (intrinsic) tracheomalacia in children (2012) · Cochrane
no estimate extracted1 study · 38 participantsLow
Human deoxyribonuclease vs placebo
Difficulty expectorating sputum score (change from baseline) · children with primary (intrinsic) tracheomalacia
Interventions for primary (intrinsic) tracheomalacia in children (2012) · Cochrane
no estimate extracted1 study · 38 participantsLow
Human deoxyribonuclease vs placebo
Lung function: FVC % predicted (baseline to end point) · children with primary (intrinsic) tracheomalacia
Interventions for primary (intrinsic) tracheomalacia in children (2012) · Cochrane
no estimate extracted1 study · 27 participantsLow
Human deoxyribonuclease vs placebo
Lung function: FEV1 % predicted (baseline to end point) · children with primary (intrinsic) tracheomalacia
Interventions for primary (intrinsic) tracheomalacia in children (2012) · Cochrane
no estimate extracted1 study · 27 participantsLow
Intervention NR
Overall five year survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.9 [0.84, 0.95]2 studies · 36858 participantsVery low
Intervention NR
Permanent stoma rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.57 [0.35, 0.92]2 studies · 7093 participantsVery low
Intervention NR
Abdominoperineal excision of the rectum rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.55 [0.42, 0.72]1 study · 894 participantsVery low
Intervention NR
Overall five year survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.87 [0.82, 0.92]2 studies · 15462 participantsLow
Intervention NR
Overall five year survival ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.84 [0.76, 0.93]1 study · 2905 participantsLow
Intervention NR
Overall five year survival ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.99 [0.86, 1.14]1 study · 1903 participantsLow
Intervention NR
Five year disease specific survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.94 [0.78, 1.13]1 study · 1416 participantsLow
Intervention NR
Inpatient and 30 day mortality ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.79 [0.61, 1.02]3 studies · 47584 participantsVery low
Intervention NR
Inpatient and 30 day mortality ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.79 [0.51, 1.22]1 study · 1903 participantsLow
Intervention NR
Anastomotic leak rate ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.66 [0.36, 1.21]1 study · 2570 participantsLow
Intervention NR
Anastomotic leak rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.61 [0.29, 1.28]1 study · 1929 participantsLow
Intervention NR
Overall five year survival ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.97 [0.77, 1.22]2 studies · 5211 participantsVery low
Intervention NR
Permanent stoma rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.65 [0.46, 0.91]1 study · 1323 participantsLow
Intervention NR
Abdominoperineal excision of rectum rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.2 [0.1, 0.4]1 study · 180 participantsVery low
Intervention NR
Overall five year survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.81 [0.71, 0.94]4 studies · 14628 participantsLow