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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Every word you type has to appear somewhere in the question, and the closest matches are ranked first.

Limit to evidence status or GRADE (optional)

75,239 questions in 5,342 reviews

current versions
No studies 15,213 · 20.2%Ungraded 10,323 · 13.7%Very low 17,528 · 23.3%Low 17,951 · 23.9%Moderate 11,190 · 14.9%High 3,034 · 4%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Intervention NR
Five year disease specific survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.74 [0.62, 0.88]1 study · 2186 participantsLow
Intervention NR
Inpatient and 30 day mortality ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.74 [0.6, 0.91]2 studies · 11973 participantsLow
Intervention NR
Five year local recurrence rate ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.56 [0.44, 0.71]1 study · 2587 participantsLow
Intervention NR
Anastomotic leak rate ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.71 [0.31, 1.63]2 studies · 8563 participantsVery low
Intervention NR
Permanent stoma rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.7 [0.53, 0.94]1 study · 2026 participantsLow
Intervention NR
Overall five year survival ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.85 [0.77, 0.95]3 studies · 4028 participantsLow
Intervention NR
Inpatient and 30 day mortality ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.98 [0.79, 1.2]3 studies · 77823 participantsVery low
Intervention NR
Inpatient and 30 day mortality ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.89 [0.78, 1.01]7 studies · 263071 participantsVery low
Intervention NR
Inpatient and 30 day mortality ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 1.07 [0.76, 1.5]5 studies · 14941 participantsVery low
Intervention NR
Five year local recurrence rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
HR 0.77 [0.51, 1.16]3 studies · 2986 participantsVery low
Intervention NR
Anastomotic leak rate ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 1.44 [0.8, 2.59]1 study · 2808 participantsLow
Intervention NR
Anastomotic leak rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery
Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane
OR 0.72 [0.48, 1.09]2 studies · 2615 participantsLow
Pre‐operative biliary drainage vs direct surgery
Mortality · patients with obstructive jaundice.
Pre‐operative biliary drainage for obstructive jaundice (2012) · Cochrane
RR 1.12 [0.73, 1.71]6 studies · 520 participantsVery low
Pre‐operative biliary drainage vs direct surgery
Morbidity ICH‐GCP classification · patients with obstructive jaundice.
Pre‐operative biliary drainage for obstructive jaundice (2012) · Cochrane
Rate ratio 1.66 [1.28, 2.16]6 studies · 503 participantsVery low
Intervention NR
All‐cause mortality (ticlopidine vs placebo) · patients with type 2 diabetes mellitus
Adenosine‐diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2… (2012) · Cochrane
RR 1.29 [0.71, 2.32]1 study · 335 participantsModerate
Intervention NR
Vascular mortality (ticlopidine vs placebo) · patients with type 2 diabetes mellitus
Adenosine‐diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2… (2012) · Cochrane
RR 0.94 [0.47, 1.88]1 study · 335 participantsModerate
Intervention NR
Myocardial infarction (fatal and non‐fatal) (ticlopidine vs placebo) · patients with type 2 diabetes mellitus
Adenosine‐diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2… (2012) · Cochrane
RR 0.78 [0.39, 1.57]1 study · 335 participantsModerate
Intervention NR
Stroke (fatal and non‐fatal) (a. ticlopidine vs aspirin) (b. clopidogrel vs aspirin & dipyramidole) · patients with type 2 diabetes mellitus
Adenosine‐diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2… (2012) · Cochrane
RR 0.56 [0.37, 0.94]1 study · 597 participantsModerate
Intervention NR
Health‐related quality of life · patients with type 2 diabetes mellitus
Adenosine‐diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2… (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Adverse effects · patients with type 2 diabetes mellitus
Adenosine‐diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2… (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Costs · patients with type 2 diabetes mellitus
Adenosine‐diphosphate (ADP) receptor antagonists for the prevention of cardiovascular disease in type 2… (2012) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Stillbirths · pregnant women giving birth
Traditional birth attendant training for improving health behaviours and pregnancy outcomes (2012) · Cochrane
RR 0.99 [0.76, 1.28]2 studies · 27594 participantsModerate
Intervention NR
Early neonatal death (0 to 6 days) · pregnant women giving birth
Traditional birth attendant training for improving health behaviours and pregnancy outcomes (2012) · Cochrane
RR 0.83 [0.68, 1.01]3 studies · 37494 participantsModerate
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
Anastomotic leak Odds ratio · patients with Bowel resection
Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane
OR 0.76 [0.44, 1.32]7 studies · 842 participantsVery low
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
Anastomosis time Mean difference · patients with Bowel resection
Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane
no estimate extracted2 studies · 218 participantsLow
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
Length of hospital stay Mean difference · patients with Bowel resection
Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane
no estimate extracted3 studies · 390 participantsLow
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
Mortality Odds ratio · patients with Bowel resection
Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane
OR 0.56 [0.19, 1.63]4 studies · 403 participantsLow
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
Major complications Odds ratio · patients with Bowel resection
Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane
OR 0.71 [0.44, 1.16]7 studies · 842 participantsLow
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
Anastomotic leak in high quality trials Odds ratio · patients with Bowel resection
Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane
OR 1.13 [0.42, 3.01]3 studies · 353 participantsModerate
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
Anastomotic leak in poor quality trials Odds ratio · patients with Bowel resection
Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane
OR 0.63 [0.32, 1.24]4 studies · 489 participantsVery low
Intervention NR
Incident reporting rate · healthcare professionals
Interventions to increase clinical incident reporting in health care (2012) · Cochrane
no estimate extracted4 studies · 4 participantsVery low
Dialectical Behaviour Therapy (DBT) vs treatment
BPD total severity ‐ DBT vs. TAUmean number of BPD criteria met · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted1 study · 20 participantsLow
Dialectical Behaviour Therapy (DBT) vs general management (GM) according to APA guidelines
Inappropriate anger ‐ DBT vs. GMSTAXI3‐anger out · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted1 study · 180 participantsModerate
Dialectical Behaviour Therapy (DBT) vs general management (GM) according to APA guidelines
Parasuicidality ‐ DBT vs. GMmean no. of suicidal and self‐injurious episodes · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted1 study · 180 participantsModerate
Dialectical Behaviour Therapy (DBT) vs general management (GM) according to APA guidelines
Interpersonal problems ‐ DBT vs. GMIIP‐C4 total · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted1 study · 180 participantsModerate
Dialectical Behaviour Therapy (DBT) vs community treatment by experts (CTBE)
SuicidalitySBQ1 · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted1 study · 89 participantsLow
Dialectical Behaviour Therapy for BPD with post‐traumatic stress disorder (DBT‐PTSD) vs waiting list (WL)
BPD total severityBSL1 · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted1 study · 31 participantsLow
Dialectical Behaviour Therapy for BPD with post‐traumatic stress disorder (DBT‐PTSD) vs waiting list (WL)
DissociationDES3 · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted1 study · 30 participantsLow
Mentalisation‐Based Treatment‐partial hospitalisation (MBT‐PH) vs treatment
Suicidalityno. of participants with suicide attempt (last 6 months) · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
RR 0.08 [0.01, 0.58]1 study · 38 participantsLow
Mentalisation‐Based Treatment‐partial hospitalisation (MBT‐PH) vs treatment
Parasuicidalityno. of participants with self‐mutilating behaviour (last 6 months) · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
RR 0.44 [0.24, 0.81]1 study · 38 participantsLow
Mentalisation‐Based Treatment‐partial hospitalisation (MBT‐PH) vs treatment
Interpersonal problemsIIP2 · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted1 study · 38 participantsLow
Mentalisation‐Based Treatment‐outpatient (MBT‐out) vs treatment
Suicidalityno. of participants with life‐threatening suicide attempts (last 6 months) · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
RR 0.11 [0.03, 0.46]1 study · 134 participantsModerate
Dialectical Behaviour Therapy (DBT) vs treatment
Inappropriate anger ‐ DBT vs. TAUSTAXI2 anger out, STAXI anger trait · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted2 studies · 46 participantsLow
Mentalisation‐Based Treatment‐outpatient (MBT‐out) vs treatment
Parasuicidalityno. of participants with self‐harm incidents (last 6 months) · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
RR 0.56 [0.34, 0.92]1 study · 134 participantsModerate
Mentalisation‐Based Treatment‐outpatient (MBT‐out) vs treatment
Interpersonal problemsIIP2 · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted1 study · 134 participantsModerate
Transference‐Focused Psychotherapy (TFP) vs community treatment by experts (CTBE)
BPD total severitymean number of BPD criteria met. Scale from: 0 to 9. · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
no estimate extracted1 study · 104 participantsModerate
Transference‐Focused Psychotherapy (TFP) vs community treatment by experts (CTBE)
Suicidalityno. of participants with suicidal act (last 12 months) · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
RR 0.64 [0.27, 1.51]1 study · 104 participantsModerate
Transference‐Focused Psychotherapy (TFP) vs community treatment by experts (CTBE)
Parasuicidalityno. of participants with self‐harming behaviour (last 12 months) · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
RR 1.09 [0.84, 1.4]1 study · 104 participantsModerate
Cognitive‐Behavioural Therapy (CBT) vs treatment
Suicidality ‐ CBT vs. TAUno. of participants with suicidal act (last 12 months) · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
RR 0.78 [0.47, 1.27]1 study · 101 participantsModerate
Cognitive‐Behavioural Therapy (CBT) vs treatment
Parasuicidality ‐ CBT vs. TAUno. of participants with self‐harming behaviour (last 12 months) · patients with borderline personality disorder
Psychological therapies for people with borderline personality disorder (2012) · Cochrane
RR 1.17 [0.86, 1.6]1 study · 99 participantsModerate