Cochrane · systematic review · CD005477

Single layer versus double layer suture anastomosis of the gastrointestinal tract

Sajid, MS, Siddiqui, MRS, Baig, MK · Cochrane Database of Systematic Reviews · 2012 · Cochrane Library

ColorectalAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
7
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 28.6%Low 4 · 57.1%Moderate 1 · 14.3%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Single layer gastrointestinal anastomosis compared to Double layer gastrointestinal anastomosis for Bowel resection

Population: patients with Bowel resection
7 questions
OutcomeEffectEvidenceStatus / GRADE
Anastomotic leak Odds ratio
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
OR 0.76 [0.44, 1.32]7 studies · 842 participantsVery low
Downgraded: risk of bias
Anastomosis time Mean difference
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
no estimate extracted2 studies · 218 participantsLow
Downgraded: risk of bias
Length of hospital stay Mean difference
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
no estimate extracted3 studies · 390 participantsLow
Mortality Odds ratio
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
OR 0.56 [0.19, 1.63]4 studies · 403 participantsLow
Major complications Odds ratio
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
OR 0.71 [0.44, 1.16]7 studies · 842 participantsLow
Anastomotic leak in high quality trials Odds ratio
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
OR 1.13 [0.42, 3.01]3 studies · 353 participantsModerate
Anastomotic leak in poor quality trials Odds ratio
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis
OR 0.63 [0.32, 1.24]4 studies · 489 participantsVery low