Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Combination of intraperitoneal lidocaine instillation and… may leads to lower number of women requiring rescue medication compared with placebo (low certainty).
1 finding from 1 review
RR 0.11 [0.03, 0.42]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Combination of lidocaine intraperitoneal instillation plus… showed no clear difference in number of women requiring rescue medication compared with lidocaine intraperitoneal instillation alone (low certainty).
1 finding from 1 review
RR 0.5 [0.1, 2.43]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Combination of lidocaine intraperitoneal instillation plus… may leads to lower number of women requiring rescue medication compared with intramuscular morphine alone (low certainty).
1 finding from 1 review
RR 0.11 [0.03, 0.42]
Studies not reported
Low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
EMLA cream may leads to lower number of women requiring rescue medication compared with placebo (low certainty).
1 finding from 1 review
RR 0.36 [0.25, 0.53]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
It is very uncertain whether lidocaine instillation changes adverse events within 48 hours post operation compared with placebo (very low certainty).
1 finding from 1 review
RR 1.04 [0.4, 2.69]
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Lidocaine instillation may leads to lower number of women requiring rescue medication compared with placebo (low certainty).
1 finding from 1 review
RR 0.27 [0.17, 0.44]
Studies not reported
Low
Intraperitoneal pain (NRS; higher = more pain) · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Adverse events within 48 hours post operation · women undergoing PPTL under local anaesthesia
1 finding from 1 review
no estimate extracted
Studies not reported
Very low
Number of women requiring rescue medication · women undergoing PPTL under local anaesthesia
Intramuscular morphine showed no clear difference in number of women requiring rescue medication compared with placebo (low certainty).
1 finding from 1 review
RR 1 [0.81, 1.23]
Studies not reported
Low
Injection site pain · Patients requiring local anaesthesia
1 finding from 1 review
Personal preference · Patients requiring local anaesthesia
Plain lidocaine leads to higher preference compared with buffered lidocaine (high certainty).
1 finding from 1 review
Adverse events · Patients requiring local anaesthesia
1 finding from 1 review
At least 50% reduction in pain · Patients requiring surgical removal of a lower wisdom tooth or teeth, with baseline moderate to severe pain (surgery under local…
Paracetamol (single oral dose, any dose or formulation; subgroups up… led to higher achieving at least 50% pain relief at 4 hours (using pain intensity… compared with placebo; GRADE not reported.
3 findings from 1 review
RR 4.87 [2.83, 8.37]
17 studies · 1658 participants
GRADE not reported
RR 3.41 [2.34, 4.97]
13 studies · 1184 participants
GRADE not reported
RR 2.85 [1.89, 4.29]
16 studies · 1498 participants
GRADE not reported