Treatment withdrawal · patients with drug‐resistant epilepsy
Nimodipine showed no clear difference in treatment withdrawal Number of withdrawals compared with placebo (moderate certainty).
1 finding from 1 review
Treatment failure · Patients with presumed drug‐sensitive TB
1 finding from 1 review
Treatment failure · Patients with presumed drug‐sensitive TB
1 finding from 1 review
Treatment failure · Patients with presumed drug‐sensitive TB
1 finding from 1 review
Amputation · patients with in‐stent restenosis of the femoropopliteal arteries
1 finding from 1 review
Target lesion revascularization · patients with in‐stent restenosis of the femoropopliteal arteries
It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes target lesion revascularization (TLR) compared with uncoated balloon angioplasty at 6 months (very low certainty).
1 finding from 1 review
Binary restenosis · patients with in‐stent restenosis of the femoropopliteal arteries
It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes binary restenosis compared with uncoated balloon angioplasty at 6 months (very low certainty).
1 finding from 1 review
Death · patients with in‐stent restenosis of the femoropopliteal arteries
It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes death compared with uncoated balloon angioplasty at 6 months (very low certainty).
1 finding from 1 review
Improvement ≥ 1 Rutherford category · patients with in‐stent restenosis of the femoropopliteal arteries
It is very uncertain whether drug‐eluting balloon angioplasty at 6 months changes improvement ≥ 1 Rutherford category compared with uncoated balloon angioplasty at 6 months (very low certainty).
1 finding from 1 review
Total mortality Mean duration of 3.8 years · adults 60 years or older with primary hypertension
Antihypertensive drug leads to lower total mortality Mean duration of 3.8 years compared with placebo or no treatment (high certainty).
1 finding from 1 review
Cardiovascular mortality and morbidity Mean duration of 3.7 years · adults 60 years or older with primary hypertension
Antihypertensive drug probably leads to lower cardiovascular mortality and morbidity Mean duration of 3.7 years compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Cerebrovascular mortality + morbidity · adults 60 years or older with primary hypertension
Antihypertensive drug probably leads to lower cerebrovascular mortality and morbidity Mean duration of 3.7 years compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Coronary heart disease mortality + morbidity · adults 60 years or older with primary hypertension
Antihypertensive drug probably leads to lower coronary heart disease mortality and morbidity Mean duration of 2.9… compared with placebo or no treatment (moderate certainty).
1 finding from 1 review
Withdrawals due to adverse events · adults 60 years or older with primary hypertension
Antihypertensive drug may leads to higher withdrawals due to adverse effects Mean duration of 4.6 years compared with placebo or no treatment (low certainty).
1 finding from 1 review
Time from beginning of treatment until death or full‐time ventilation · adults with SMA types II and III
1 finding from 1 review
Adverse events related to treatment · adults with SMA types II and III
1 finding from 1 review
Time from beginning of treatment until death or full‐time ventilation · children and adults with SMA types II and III
1 finding from 1 review
Adverse events related to treatment · children and adults with SMA types II and III
1 finding from 1 review
Time from beginning of treatment until death or full‐time ventilation · children with SMA type II
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Adverse events related to treatment · children with SMA type II
Intrathecal injected nusinersen showed no clear difference in adverse events related to treatment compared with sham procedure (moderate certainty).
1 finding from 1 review