Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

382 questions · 384 findings · 98 reviews

No studies found 54 · 14.1%GRADE not reported 37 · 9.6%Very low 116 · 30.2%Low 99 · 25.8%Moderate 60 · 15.6%High 18 · 4.7%

MI vs TAU

Successful discontinuation of BZDs‐ post treatment Objective and subjective · patients with BZD harmful use, abuse or dependence

It is very uncertain whether MI changes successful discontinuation of BZDs‐ post treatment Objective and… compared with TAU (very low certainty).

2 findings from 1 review

Intervention not reported

Discontinuation: other personal reasons (12 months) · women aged ≤ 25 years with desire for contraception

It is very uncertain whether the intervention changes discontinuation: other personal reasons (12 months) (very low certainty).

1 finding from 1 review

Adalimumab every other week vs placebo

Treatment discontinuation · participants with hidradenitis suppurativa

Adalimumab every other week showed no clear difference in frequency of treatment discontinuation compared with placebo (high certainty).

1 finding from 1 review

Adalimumab weekly vs placebo

Treatment discontinuation · participants with hidradenitis suppurativa

Adalimumab weekly showed no clear difference in frequency of treatment discontinuation compared with placebo (moderate certainty).

1 finding from 1 review

Topical foscarnet vs placebo

Adverse effects during use of the preventative intervention (leading to discontinuation) · participants with recurrent herpes labialis

Topical foscarnet showed no clear difference in adverse effects during use of the preventative intervention (leading… compared with placebo (moderate certainty).

1 finding from 1 review

FAE vs MTX

Common nuisance AEs (not leading to treatment discontinuation) · psoriasis

It is very uncertain whether FAE changes common nuisance AEs (not leading to treatment discontinuation) compared with MTX (very low certainty).

1 finding from 1 review

FAE vs placebo

Common nuisance AEs (not leading to treatment discontinuation) · psoriasis

FAE probably leads to higher common nuisance AEs (not leading to treatment discontinuation) compared with placebo (moderate certainty).

1 finding from 1 review

FAE vs MTX

Withdrawals due to adverse events · psoriasis

It is very uncertain whether FAE changes AEs leading to treatment discontinuation compared with MTX (very low certainty).

1 finding from 1 review

Intervention not reported

Discontinuation due to adverse events · Patients with fibromyalgia

It is very uncertain whether the intervention changes discontinuation due to adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Discontinuations due to adverse events · patients with rheumatoid arthritis

The intervention leads to higher discontinuations due to adverse events (high certainty).

1 finding from 1 review

TCu 220C vs Copper 7

Discontinuation due to pregnancy (750 days) · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to pregnancy (750 days) compared with copper 7 (moderate certainty).

1 finding from 1 review

TCu 220C vs Copper 7

Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to expulsion (750 days) compared with copper 7 (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to perforation · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to perforation (750 days) Tietze‐Potter gross… compared with lippes Loop (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to pelvic inflammation · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to pelvic inflammatory disease (750 days) compared with lippes Loop (moderate certainty).

1 finding from 1 review