White spot lesions assessed by laser fluorescence (DIAGNOdent) · Patients undergoing fixed orthodontic (fixed appliance) treatment (adolescents and adults, ages 12 to 35)
A single small split-mouth RCT found the nCaF2-containing primer reduced demineralization (DIAGNOdent) but showed no significant clinical white spot lesion difference at debonding (ungraded).
1 finding from 1 review
Overall success (composite of clinical and radiographic success) · Adults aged 18 years or older with mature permanent teeth and carious pulp exposure
Partial pulpotomy with MTA or Biodentine had a pooled success rate of 86.8%.
1 finding from 1 review
Whitening (bleaching) efficacy · Demineralised / white-spot-lesion enamel (in vitro specimens)
Low-quality in vitro evidence indicates that adding fluoride or other remineralising agents does not impair the whitening/bleaching effect (ungraded).
1 finding from 1 review
Enamel mineral loss / remineralisation · Demineralised / white-spot-lesion enamel (in vitro specimens)
Low-quality in vitro evidence indicates that adding fluoride, calcium or CPP-ACP to bleaching agents can reduce enamel mineral loss (ungraded).
1 finding from 1 review
Enamel remineralization extent · Human enamel specimens around orthodontic brackets (in vitro)
In vitro, a nano-CaF2-containing orthodontic cement showed significant enamel remineralization versus control in a single study (ungraded).
1 finding from 1 review
Enamel remineralization extent · Human enamel specimens around orthodontic brackets (in vitro)
In vitro, n-ACP-containing orthodontic adhesives showed significant enamel remineralization versus control in both studies, but evidence is weak (only 2 studies; ungraded).
1 finding from 1 review
Enamel remineralization extent and color change · Human enamel specimens around orthodontic brackets (in vitro)
In vitro, an n-AFCP-containing orthodontic primer showed significant enamel remineralization and less color change versus control in a single study (ungraded).
1 finding from 1 review
Postoperative hypersensitivity (POH), patient-reported (dichotomous yes/no) · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
Dental cavity liner (e.g. calcium hydroxide, glass ionomer,… showed no clear difference in postoperative hypersensitivity (POH), patient-reported (dichotomous… compared with no liner (resin-based composite bonded directly to the tooth) (low certainty).
3 findings from 1 review
RR 0.56 [0.26, 1.17]
3 studies
Low
RR 0.26 [0.11, 0.64]
1 study
GRADE not reported
RR 0.44 [0.15, 1.34]
3 studies
GRADE not reported
Postoperative hypersensitivity (POH), cold response measurement (time in seconds) · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
Dental cavity liner (e.g. calcium hydroxide, glass ionomer,… may leads to higher postoperative hypersensitivity (POH), cold response measurement… compared with no liner (resin-based composite bonded directly to the tooth) (low certainty).
1 finding from 1 review
MD 6 [1.36, 10.64]
1 study
Low
Restoration failure · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
2 findings from 1 review
Cost of materials · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
1 finding from 1 review
Postoperative hypersensitivity (POH), cold response measurement (VAS score) · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
Dental cavity liner (e.g. calcium hydroxide, glass ionomer,… showed no clear difference in postoperative hypersensitivity (POH), cold response measurement (VAS… compared with no liner (resin-based composite bonded directly to the tooth); GRADE not reported.
2 findings from 1 review
MD -0.20 [-0.67, 0.26]
2 studies
GRADE not reported
MD -0.33 [-0.76, 0.11]
2 studies
GRADE not reported
Postoperative hypersensitivity (POH), patient-reported (VAS score) · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
Dental cavity liner (e.g. calcium hydroxide, glass ionomer,… led to lower postoperative hypersensitivity (POH), patient-reported (VAS score) compared with no liner (resin-based composite bonded directly to the tooth); GRADE not reported.
2 findings from 1 review
MD -0.33 [-0.43, -0.23]
1 study
GRADE not reported
MD -0.20 [-0.31, -0.09]
1 study
GRADE not reported
Adverse events · Adults or children with a Class I or Class II resin-based composite restoration in a permanent posterior tooth
The review found no eligible studies for this question.
1 finding from 1 review
Restoration longevity · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
Cavity liners may make little or no difference to restoration longevity (high success across groups; low certainty).
1 finding from 1 review
Treatment failure · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
The evidence is very uncertain about the effect of cavity liners on treatment failure; no significant difference between lined and unlined (or differently lined) restorations was found (very low certainty).
1 finding from 1 review
Postoperative hypersensitivity (POH), patient-reported (VAS score) · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
The evidence is very uncertain whether cavity liners reduce postoperative hypersensitivity; no significant difference was found overall (very low certainty).
1 finding from 1 review
Tooth survival · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
Cavity liners may make little or no difference to tooth survival (99.4% survival across groups; low certainty).
1 finding from 1 review
Oral health-related quality of life · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
No included study reported oral health-related quality of life (a planned outcome), so no evidence is available.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Secondary prevention of caries · Patients with deep caries lesions in mature or immature permanent (posterior) teeth, with no symptoms or reversible pulpitis
Cavity liners may make little or no difference to secondary caries prevention (~100% prevention across groups; low certainty).
1 finding from 1 review