Question · asked by 1 review
Bleaching gel with added remineralising agent (fluoride, calcium, or CPP-ACP) vs Bleaching alone (no remineralising agent): Whitening (bleaching) efficacy
- Population
- Demineralised / white-spot-lesion enamel (in vitro specimens)
- Intervention
- Bleaching gel with added remineralising agent (fluoride, calcium, or CPP-ACP)
- Comparison
- Bleaching alone (no remineralising agent)
- Outcome
- Whitening (bleaching) efficacy
Low-quality in vitro evidence indicates that adding fluoride or other remineralising agents does not impair the whitening/bleaching effect (ungraded).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Bleaching gel with added remineralising agent (fluoride, calcium, or CPP-ACP) vs Bleaching alone (no remineralising agent) Whitening (bleaching) efficacy · Demineralised / white-spot-lesion enamel (in vitro specimens) · In vitro laboratory studies Low-quality in vitro evidence indicates that adding fluoride or other remineralising agents does not impair the whitening/bleaching effect (ungraded). Is Bleaching Effective in Managing Post-orthodontic White-spot Lesions? A Systematic Review. (2020) All outcomes | Low-quality in vitro data indicated that the presence of fluoride or any other remineralising agent did not impair the whitening effect. | 3 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Is Bleaching Effective in Managing Post-orthodontic White-spot Lesions? A Systematic Review. 2020 All outcomes | 2018-07-01 | 15 | Low / Critically Low |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.