Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,703 questions · 3,824 findings · 858 reviews

No studies found 573 · 15%GRADE not reported 383 · 10%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs no intervention or control intervention (control)

Normalcy of diet (total parenteral nutrition) · All patients with cancer who are receiving treatment

It is very uncertain whether oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed… changes normalcy of diet (days of total parenteral nutrition, TPN) compared with control (no treatment or standard/usual oral care, e.g. saline rinse) (very low certainty).

2 findings from 1 review

Oral cryotherapy (ice chips, ice-cold water, ice cubes or crushed ice held in the mouth during cancer treatment) vs no intervention or control intervention (control)

Number of days unable to take medicine orally · All patients with cancer who are receiving treatment

The review found no eligible studies for this question.

1 finding from 1 review

Sucralfate suspension (topical) vs Placebo suspension

Number of painful days · People with Behcet's disease with a history of recurrent oral aphthous-type (RAS-type) ulcers diagnosed clinically; primary care

Sucralfate suspension (topical) showed no clear difference in number of painful days compared with placebo suspension; GRADE not reported.

1 finding from 1 review

Erdosteine vs no treatment

FEV1 · people with bronchiectasis

Erdosteine may leads to higher lung function change in FEV1 (L) at day 15 compared with no treatment (low certainty).

1 finding from 1 review

TCu 220C vs Copper 7

Discontinuation due to pregnancy (750 days) · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to pregnancy (750 days) compared with copper 7 (moderate certainty).

1 finding from 1 review

TCu 220C vs Copper 7

Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to expulsion (750 days) compared with copper 7 (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to perforation · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to perforation (750 days) Tietze‐Potter gross… compared with lippes Loop (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to pelvic inflammation · patients with Immediate insertion Post abortion

TCu 220C showed no clear difference in discontinuation due to pelvic inflammatory disease (750 days) compared with lippes Loop (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to pregnancy (750 days) · patients with Immediate insertion Post abortion

TCu 220C probably leads to lower discontinuation rate due to pregnancy (750days) compared with lippes Loop (moderate certainty).

1 finding from 1 review

TCu 220C vs Lippes Loop

Discontinuation due to expulsion (750 days) · patients with Immediate insertion Post abortion

TCu 220C probably leads to lower discontinuation rate due to expulsion (750 days) Tietze‐Potter gross… compared with lippes Loop (moderate certainty).

1 finding from 1 review

Nocturnal ventilation vs no ventilation

No improvement of daytime hypercapnia: long‐term · patients with neuromuscular and chest wall disorders and chronic hypoventilation

It is very uncertain whether nocturnal ventilation changes no improvement of daytime hypercapnia: long‐term compared with no ventilation (very low certainty).

1 finding from 1 review

Volume‐cycled ventilation vs pressure‐cycled ventilation

No improvement of daytime hypercapnia: long‐term ‐ not measured · patients with neuromuscular and chest wall disorders and chronic hypoventilation

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Days in hospital · Patients with dengue‐related shock
1 finding from 1 review

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

Early onset GBS disease (sepsis and/or meningitis within the first seven days of life)) · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes early onset GBS disease (sepsis and/or meningitis within the first… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Chlorhexidine (vaginal wash or gel/cream) vs placebo or no treatment

GBS pneumonia within the first seven days of life · women with vaginal or rectal colonization with GBS during labour and their preterm/term infants

It is very uncertain whether chlorhexidine (vaginal wash or gel/cream) changes GBS pneumonia within the first seven days of life compared with placebo or no treatment (very low certainty).

1 finding from 1 review