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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
1,956 questions in 143 reviews · Musculoskeletal
current versionsNo studies 555 · 28.4%Ungraded 107 · 5.5%Very low 255 · 13%Low 555 · 28.4%Moderate 357 · 18.3%High 127 · 6.5%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Flexibility exercise training vs aerobic exercise training Withdrawals All‐cause attrition · adults with fibromyalgia Flexibility exercise training for adults with fibromyalgia (2019) · Cochrane | RR 0.97 [0.61, 1.55] | 5 studies · 301 participants | Ungraded |
Flexibility exercise training vs aerobic exercise training Adverse events—increase in symptoms, injuries, or serious adverse events · adults with fibromyalgia Flexibility exercise training for adults with fibromyalgia (2019) · Cochrane | no estimate extracted | NR | Very low |
Surgery vs non‐operative treatment Pain (VAS) from 0 to 10, 0 is no pain · people with full‐thickness rotator cuff tears Surgery for rotator cuff tears (2019) · Cochrane | no estimate extracted | 3 studies · 258 participants | Moderate |
Surgery vs non‐operative treatment Functional outcome (Constant score) from 0 to 100, 100 is best) · people with full‐thickness rotator cuff tears Surgery for rotator cuff tears (2019) · Cochrane | no estimate extracted | 3 studies · 269 participants | Low |
Surgery vs non‐operative treatment Participant‐rated global assessment of treatment success at 12 months · people with full‐thickness rotator cuff tears Surgery for rotator cuff tears (2019) · Cochrane | RR 1.08 [0.96, 1.22] | 1 study · 110 participants | Low |
Surgery vs non‐operative treatment Health‐related quality of life (SF‐36 mental component) from 0‐100; 100 is best) · people with full‐thickness rotator cuff tears Surgery for rotator cuff tears (2019) · Cochrane | no estimate extracted | 1 study · 103 participants | Low |
Surgery vs non‐operative treatment Adverse events · people with full‐thickness rotator cuff tears Surgery for rotator cuff tears (2019) · Cochrane | no estimate extracted | 1 study · 103 participants | Very low |
Surgery vs non‐operative treatment Serious adverse events · people with full‐thickness rotator cuff tears Surgery for rotator cuff tears (2019) · Cochrane | no estimate extracted | NR | Very low |
Exercise vs no exercise Hand function ‐ short term (less than 3 months) Grip function test scale of 0 to 80 points (higher score indicates better grip function) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 1 study · 24 participants | Very low |
Exercise vs no exercise Hand impairment ‐ power grip strength of both hands (kg) ‐ long term (12 months and beyond) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 1 study · 355 participants | High |
Exercise vs no exercise Hand impairment ‐ pinch grip strength (kg) ‐ left hand ‐ short term (less than 3 months) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 2 studies · 120 participants | Very low |
Exercise vs no exercise Hand impairment ‐ pinch grip strength (kg) ‐ right hand ‐ short term (less than 3 months) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 2 studies · 120 participants | Very low |
Exercise vs no exercise Hand impairment ‐ pinch grip strength of both hands (kg) ‐ medium term (3 to 11 months) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 1 study · 396 participants | High |
Exercise vs no exercise Hand impairment ‐ pinch grip strength of both hands (kg) ‐ long term (12 months and beyond) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 1 study · 351 participants | High |
Exercise vs no exercise ACR50 response · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 0 studies · 0 participants | Ungraded |
Exercise vs no exercise Participant adherence ‐ medium term (3 to 11 months) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | RR 1.31 [1.15, 1.48] | 1 study · 438 participants | Moderate |
Exercise vs no exercise Participant adherence ‐ long term (12 months and beyond) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | RR 1.09 [0.93, 1.28] | 1 study · 422 participants | Moderate |
Exercise vs no exercise Adverse events due to exercise · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 1 study · 490 participants | Moderate |
Exercise vs no exercise Hand function ‐ medium term (3 to 11 months) Overall hand function subscale of the Michigan Hand Questionnaire, 0 to 100 (higher scores mean better hand function) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 1 study · 449 participants | Moderate |
Exercise vs no exercise Hand function ‐ long term (12 months and beyond) Overall hand function subscale of the Michigan Hand Questionnaire, 0 to 100 (higher scores mean better hand function) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 1 study · 438 participants | Moderate |
Exercise vs no exercise Pain ‐ short term (less than 3 months) visual analogue scale (0 to 100 mm, higher score means more pain) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 2 studies · 124 participants | Very low |
Exercise vs no exercise Pain ‐ medium term (3 to 11 months) Pain subscale of Michigan Hand Outcomes Questionnaire (0 to 100 points, higher score means more pain) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 1 study · 445 participants | Moderate |
Exercise vs no exercise Pain ‐ long term (12 months and beyond) Pain subscale of Michigan Hand Outcomes Questionnaire (0 to 100 points, higher score means more pain) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 1 study · 437 participants | Moderate |
Exercise vs no exercise Hand impairment ‐ power grip strength (kg) ‐ left hand ‐ short term (less than 3 months) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 3 studies · 141 participants | Very low |
Exercise vs no exercise Hand impairment ‐ power grip strength (kg) ‐ right hand ‐ short term (less than 3 months) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 3 studies · 141 participants | Very low |
Exercise vs no exercise Hand impairment ‐ power grip strength of both hands (kg) ‐ medium term (3 to 11 months) · rheumatoid arthritis of the hand Exercise for rheumatoid arthritis of the hand (2018) · Cochrane | no estimate extracted | 1 study · 400 participants | High |
Intervention NR Pain Scale from: 0 to 10, 0 is no pain. · people with osteoporotic vertebral compression fracture Percutaneous vertebroplasty for osteoporotic vertebral compression fracture (2018) · Cochrane | no estimate extracted | 5 studies · 535 participants | High |
Intervention NR Disability (Roland‐Morris Disability Questionnaire) Scale from: 0 to 23; 0 is no disability. · people with osteoporotic vertebral compression fracture Percutaneous vertebroplasty for osteoporotic vertebral compression fracture (2018) · Cochrane | no estimate extracted | 4 studies · 472 participants | High |
Intervention NR Disease‐specific quality of Life (QUALEFFO) Scale from: 0 to 100; 0 is best. · people with osteoporotic vertebral compression fracture Percutaneous vertebroplasty for osteoporotic vertebral compression fracture (2018) · Cochrane | no estimate extracted | 3 studies · 351 participants | High |
Intervention NR Overall quality of Life (EQ5D) Scale from: 0 to 1; 1 is best. · people with osteoporotic vertebral compression fracture Percutaneous vertebroplasty for osteoporotic vertebral compression fracture (2018) · Cochrane | no estimate extracted | 3 studies · 285 participants | Moderate |
Intervention NR Participant global assessment of success (People perceived their pain as better) · people with osteoporotic vertebral compression fracture Percutaneous vertebroplasty for osteoporotic vertebral compression fracture (2018) · Cochrane | RR 1.4 [0.67, 2.95] | 1 study · 78 participants | Moderate |
Intervention NR Incident symptomatic vertebral fractures · people with osteoporotic vertebral compression fracture Percutaneous vertebroplasty for osteoporotic vertebral compression fracture (2018) · Cochrane | RR 1.29 [0.46, 3.62] | 6 studies · 840 participants | Low |
Intervention NR Other serious adverse events · people with osteoporotic vertebral compression fracture Percutaneous vertebroplasty for osteoporotic vertebral compression fracture (2018) · Cochrane | RR 0.61 [0.33, 1.1] | 5 studies · 821 participants | Low |
Open surgery vs steroid injection Resolution of symptoms (after one or more injections) · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | RR 1.48 [0.79, 2.76] | 2 studies · 270 participants | Very low |
Percutaneous surgery vs steroid injection Function Not measured · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | no estimate extracted | NR | No studies |
Percutaneous surgery vs steroid injection Participant global assessment of success Not measured · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | no estimate extracted | NR | No studies |
Percutaneous surgery vs steroid injection Recurrence · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | RR 0.57 [0.21, 1.59] | 5 studies · 392 participants | Very low |
Percutaneous surgery vs steroid injection Adverse events (infection, partial loss of movement, tendon or −0 injury, dysaesthesia, and skin atrophy or hypopigmentation) · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | RR 1.58 [0.91, 2.75] | 5 studies · 392 participants | Very low |
Percutaneous surgery vs steroid injection Neurovascular injury · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | RR 0.35 [0.04, 3.29] | 2 studies · 191 participants | Low |
Open surgery vs steroid injection plus hyaluronic acid injection guided by ultrasound Resolution of symptoms · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | RR 1.35 [0.98, 1.85] | 1 study · 30 participants | Very low |
Open surgery vs steroid injection plus hyaluronic acid injection guided by ultrasound Pain (short‐term) Not measured · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | no estimate extracted | NR | No studies |
Open surgery vs steroid injection plus hyaluronic acid injection guided by ultrasound Function Not measured · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | no estimate extracted | NR | No studies |
Open surgery vs steroid injection plus hyaluronic acid injection guided by ultrasound Participant global assessment of success Not measured · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | no estimate extracted | NR | No studies |
Open surgery vs steroid injection plus hyaluronic acid injection guided by ultrasound Recurrence · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | RR 0.14 [0.01, 2.55] | 1 study · 30 participants | Very low |
Open surgery vs steroid injection Pain Proportion with pain on the palm of the hand · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | RR 3.69 [1.99, 6.85] | 1 study · 105 participants | Low |
Open surgery vs steroid injection plus hyaluronic acid injection guided by ultrasound Adverse events (partial loss of movement, algodystrophic syndrome) · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | RR 3 [0.35, 25.68] | 1 study · 30 participants | Very low |
Open surgery vs steroid injection plus hyaluronic acid injection guided by ultrasound Neurovascular injury Not measured · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | no estimate extracted | NR | No studies |
Percutaneous surgery plus steroid injection vs steroid injection Resolution of symptoms (after 1 or more injections) · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | RR 1.51 [1.21, 1.9] | 1 study · 127 participants | Very low |
Percutaneous surgery plus steroid injection vs steroid injection Pain (short‐term) Not measured · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | no estimate extracted | NR | No studies |
Percutaneous surgery plus steroid injection vs steroid injection Function Not measured · patients with trigger finger Surgery for trigger finger (2018) · Cochrane | no estimate extracted | NR | No studies |