Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

331 questions · 335 findings · 40 reviews

No studies found 121 · 36.1%GRADE not reported 20 · 6%Very low 80 · 23.9%Low 58 · 17.3%Moderate 53 · 15.8%High 3 · 0.9%

Intervention not reported

Total mortality at the end of the · patients with coronary heart disease

The intervention showed no clear difference in total mortality at the end of the (moderate certainty).

1 finding from 1 review

Intervention not reported

Fatal and/or non‐fatal MI at the end of the · patients with coronary heart disease

It is very uncertain whether the intervention changes fatal and/or non‐fatal MI at the end of the (very low certainty).

1 finding from 1 review

Intervention not reported

Other fatal and/or non‐fatal cardiovascular events · patients with coronary heart disease

The intervention may leads to lower other fatal and/or non‐fatal cardiovascular events (low certainty).

1 finding from 1 review

Intervention not reported

Total revascularisations (including CABG and PCI) · patients with coronary heart disease

It is very uncertain whether the intervention changes total revascularisations (including CABG and PCI) (very low certainty).

1 finding from 1 review

Intervention not reported

Hospitalisations (cardiac‐related)at end of · patients with coronary heart disease

It is very uncertain whether the intervention changes hospitalisations (cardiac‐related)at end of (very low certainty).

1 finding from 1 review

Intervention not reported

All cause withdrawal at · patients with coronary heart disease

The intervention showed no clear difference in all cause withdrawal at (low certainty).

1 finding from 1 review

ADVICE ‐ focus on activation vs no treatment

video vs no treatment: at 1 session + 2 weeks · patients with neck pain with or without radiculopathy

ADVICE ‐ focus on activation showed no clear difference in video vs no treatment: at 1 session + 2 weeks compared with NO TREATMENT (moderate certainty).

3 findings from 1 review

SUPPORTIVE THERAPY vs PSYCHOEDUCATION

Service outcomes: Hospitalisation · patients with schizophrenia

It is very uncertain whether SUPPORTIVE THERAPY changes service outcomes: Hospitalisation compared with PSYCHOEDUCATION (very low certainty).

1 finding from 1 review

SUPPORTIVE THERAPY vs PSYCHOEDUCATION

Mental state: No clinically important improvement · patients with schizophrenia

It is very uncertain whether SUPPORTIVE THERAPY changes mental state. No clinically important improvement compared with PSYCHOEDUCATION (very low certainty).

1 finding from 1 review

SUPPORTIVE THERAPY vs PSYCHOEDUCATION

Leaving the study early · patients with schizophrenia

It is very uncertain whether SUPPORTIVE THERAPY changes leaving the study early compared with PSYCHOEDUCATION (very low certainty).

1 finding from 1 review

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Overall survival · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Trismus preventing further restorative treatment · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Trismus preventing further restorative treatment · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

Development of post-radiotherapy dental complications (caries, fractured teeth, periapical infection, periodontal disease, osteoradionecrosis) · Patients diagnosed with head and neck cancer planned to undergo any type of radiotherapy (external beam, intensity modulated,…

The review found no eligible studies for this question.

1 finding from 1 review