Cochrane · systematic review · CD004716

Supportive therapy for schizophrenia

Buckley, LA, Maayan, N, Soares‐Weiser, K, et al. · Cochrane Database of Systematic Reviews · 2015 · Cochrane Library

SchizophreniaAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
35
current version
GRADE rated
30
No studies
5
Included studies
NR
No studies 5 · 14.3%Ungraded 0 · 0%Very low 28 · 80%Low 0 · 0%Moderate 2 · 5.7%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

SUPPORTIVE THERAPY versus STANDARD CARE for schizophrenia

Population: patients with schizophrenia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Global state: Relapse
SUPPORTIVE THERAPY vs STANDARD CARE
RR 0.96 [0.44, 2.11]1 study · 54 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Service outcomes: Hospitalisation
SUPPORTIVE THERAPY vs STANDARD CARE
RR 1 [0.07, 15.08]1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Mental state: no clinically important improvement
SUPPORTIVE THERAPY vs STANDARD CARE
RR 0.95 [0.82, 1.11]2 studies · 98 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Leaving the study early
SUPPORTIVE THERAPY vs STANDARD CARE
RR 0.86 [0.53, 1.4]4 studies · 354 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
General functioning GAS
SUPPORTIVE THERAPY vs STANDARD CARE
no estimate extracted1 study · 29 participantsVery low
Downgraded: risk of bias, imprecision, indirectness, publication bias
Satisfaction with treatment: Recipient of care not satisfied with treatment
SUPPORTIVE THERAPY vs STANDARD CARE
RR 1.83 [0.75, 4.47]1 study · 44 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Quality of life WBS
SUPPORTIVE THERAPY vs STANDARD CARE
no estimate extracted1 study · 260 participantsVery low
Downgraded: risk of bias, imprecision, indirectness, publication bias

SUPPORTIVE THERAPY versus ANY OTHER PSYCHOLOGICAL OR PSYCHOSOCIAL TREATMENT for schizophrenia

Population: patients with schizophrenia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Global state: Relapse
SUPPORTIVE THERAPY vs ANY OTHER PSYCHOLOGICAL OR PSYCHOSOCIAL TREATMENT
RR 1.19 [0.66, 2.16]5 studies · 270 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Service outcomes: Hospitalisation
SUPPORTIVE THERAPY vs ANY OTHER PSYCHOLOGICAL OR PSYCHOSOCIAL TREATMENT
RR 1.82 [1.11, 2.99]4 studies · 306 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Mental state: No clinically important improvement
SUPPORTIVE THERAPY vs ANY OTHER PSYCHOLOGICAL OR PSYCHOSOCIAL TREATMENT
RR 1.27 [1.04, 1.54]3 studies · 194 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Leaving the study early
SUPPORTIVE THERAPY vs ANY OTHER PSYCHOLOGICAL OR PSYCHOSOCIAL TREATMENT
RR 1.03 [0.87, 1.21]19 studies · 1412 participantsModerate
Downgraded: risk of bias, imprecision
General functioning GAF and GAS
SUPPORTIVE THERAPY vs ANY OTHER PSYCHOLOGICAL OR PSYCHOSOCIAL TREATMENT
no estimate extracted2 studies · 78 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness
Satisfaction with treatment: Recipient of care not satisfied with treatment
SUPPORTIVE THERAPY vs ANY OTHER PSYCHOLOGICAL OR PSYCHOSOCIAL TREATMENT
RR 3.19 [1.01, 10.07]1 study · 45 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Quality of life QLS
SUPPORTIVE THERAPY vs ANY OTHER PSYCHOLOGICAL OR PSYCHOSOCIAL TREATMENT
no estimate extracted1 study · 19 participantsVery low
Downgraded: risk of bias, imprecision, indirectness, publication bias

SUPPORTIVE THERAPY versus COGNITIVE BEHAVIOURAL THERAPY for schizophrenia

Population: patients with schizophrenia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Global state: Relapse
SUPPORTIVE THERAPY vs COGNITIVE BEHAVIOURAL THERAPY
RR 1.1 [0.51, 2.41]4 studies · 181 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Service outcomes: Hospitalisation
SUPPORTIVE THERAPY vs COGNITIVE BEHAVIOURAL THERAPY
RR 1.6 [0.85, 3]3 studies · 153 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Mental state: No clinically important improvement
SUPPORTIVE THERAPY vs COGNITIVE BEHAVIOURAL THERAPY
RR 1.23 [0.89, 1.7]3 studies · 194 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Leaving the study early
SUPPORTIVE THERAPY vs COGNITIVE BEHAVIOURAL THERAPY
RR 1.05 [0.77, 1.44]12 studies · 812 participantsModerate
Downgraded: risk of bias
General functioning GAF and GAS
SUPPORTIVE THERAPY vs COGNITIVE BEHAVIOURAL THERAPY
no estimate extracted2 studies · 78 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, indirectness, publication bias
Satisfaction with treatment: Recipient of care not satisfied with treatment
SUPPORTIVE THERAPY vs COGNITIVE BEHAVIOURAL THERAPY
RR 3.19 [1.01, 10.07]1 study · 45 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Quality of life RSES
SUPPORTIVE THERAPY vs COGNITIVE BEHAVIOURAL THERAPY
no estimate extracted1 study · 65 participantsVery low
Downgraded: imprecision, indirectness, publication bias

SUPPORTIVE THERAPY versus FAMILY THERAPY for schizophrenia

Population: patients with schizophrenia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Global state: Relapse
SUPPORTIVE THERAPY vs FAMILY THERAPY
no estimate extracted2 studies · 87 participantsVery low
Downgraded: risk of bias, imprecision, inconsistency, publication bias
Service outcomes: Hospitalisation
SUPPORTIVE THERAPY vs FAMILY THERAPY
RR 1.93 [0.89, 4.17]1 study · 39 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Mental state: Episode of affective symptoms
SUPPORTIVE THERAPY vs FAMILY THERAPY
RR 1.71 [0.82, 3.6]1 study · 48 participantsVery low
Downgraded: risk of bias, imprecision, indirectness, publication bias
Leaving the study early
SUPPORTIVE THERAPY vs FAMILY THERAPY
RR 1.27 [0.56, 2.89]2 studies · 87 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
General functioning: No paid work
SUPPORTIVE THERAPY vs FAMILY THERAPY
RR 0.96 [0.57, 1.63]1 study · 39 participantsVery low
Downgraded: risk of bias, imprecision, indirectness, publication bias
Satisfaction with treatment ‐ not reported
SUPPORTIVE THERAPY vs FAMILY THERAPY
no estimate extractedNRNo studies
Quality of life ‐ not reported
SUPPORTIVE THERAPY vs FAMILY THERAPY
no estimate extractedNRNo studies

SUPPORTIVE THERAPY versus PSYCHOEDUCATION for schizophrenia

Population: patients with schizophrenia
7 questions
OutcomeEffectEvidenceStatus / GRADE
Global state: Relapse ‐ not reported
SUPPORTIVE THERAPY vs PSYCHOEDUCATION
no estimate extractedNRNo studies
Service outcomes: Hospitalisation
SUPPORTIVE THERAPY vs PSYCHOEDUCATION
RR 0.48 [0.05, 4.93]1 study · 47 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Mental state. No clinically important improvement
SUPPORTIVE THERAPY vs PSYCHOEDUCATION
RR 1.61 [0.96, 2.68]1 study · 19 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
Leaving the study early
SUPPORTIVE THERAPY vs PSYCHOEDUCATION
RR 0.57 [0.21, 1.54]2 studies · 71 participantsVery low
Downgraded: risk of bias, imprecision, publication bias
General functioning ‐ not reported
SUPPORTIVE THERAPY vs PSYCHOEDUCATION
no estimate extractedNRNo studies
Satisfaction with treatment ‐ not reported
SUPPORTIVE THERAPY vs PSYCHOEDUCATION
no estimate extractedNRNo studies
Quality of life QLS
SUPPORTIVE THERAPY vs PSYCHOEDUCATION
no estimate extracted1 study · 19 participantsVery low
Downgraded: risk of bias, imprecision, indirectness, publication bias