Findings

What do systematic reviews say?

285 questions · 327 findings · 36 reviews · Headline outcomes only

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No studies found 129 · 39.4%GRADE not reported 11 · 3.4%Very low 82 · 25.1%Low 64 · 19.6%Moderate 38 · 11.6%High 3 · 0.9%

Laparoscopic vs open appendectomy

Quality of life Scale used: 1) Gastro‐intestinal Quality of Life Index 2) SF‐36 questionnaire · patients with suspected appendicitis

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
2
2009 participants
Low

Laparoscopic vs open appendectomy

Pain (unpleasantness/intensity/palpation) · patients with suspected appendicitis

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 61 participants
Low

Laparoscopic vs open appendectomy

Surgical complications ‐ wound infection · patients with suspected appendicitis

Laparoscopic probably leads to lower wound infections (rate) compared with open appendectomy (moderate certainty).

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.25 [0.15, 0.42]
10 studies · 1245 participants
Moderate

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Mortality within the longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

It is very uncertain whether pulmonary artery perfusion with blood changes all‐cause mortality within longest compared with no perfusion during cardiopulmonary bypass (very low certainty).

1 finding from 1 review

Pulmonary artery perfusion versus no perfusion during cardiopulmonary bypass for open heart surgery in adults 2018 · Cochrane Headline outcomes only
Peto OR 1.78 [0.43, 7.4]
4 studies · 210 participants
Very low

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Number of participants with pulmonary events within longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

The review found no eligible studies for this question.

1 finding from 1 review

Pulmonary artery perfusion versus no perfusion during cardiopulmonary bypass for open heart surgery in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Participants with ≥ 1SAE within longest · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

It is very uncertain whether pulmonary artery perfusion with blood changes participants with ≥ 1SAE within longest compared with no perfusion during cardiopulmonary bypass (very low certainty).

1 finding from 1 review

Pulmonary artery perfusion versus no perfusion during cardiopulmonary bypass for open heart surgery in adults 2018 · Cochrane Headline outcomes only
RR 1.12 [0.66, 1.89]
3 studies · 180 participants
Very low

Pulmonary artery perfusion with blood vs no perfusion during cardiopulmonary bypass

Last measured PaO2/FiO2 ratio (mmHg) in all trials, irrespective of overall risk of bias · adult surgical patients with the need for cardiopulmonary bypass‐dependent heart surgery

1 finding from 1 review

Pulmonary artery perfusion versus no perfusion during cardiopulmonary bypass for open heart surgery in adults 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 119 participants
Very low

Percutaneous patellar osteosynthesis vs open surgery

Patient‐rated knee function score assessed using the Lysholm Knee Scoring Scale (0–100; 100 = best function). · adults with fractures of the patella

1 finding from 1 review

Interventions for treating fractures of the patella in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 52 participants
Very low

Percutaneous patellar osteosynthesis vs open surgery

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · adults with fractures of the patella

1 finding from 1 review

Interventions for treating fractures of the patella in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 183 participants
Very low

Percutaneous patellar osteosynthesis vs open surgery

Major adverse outcome: total events · adults with fractures of the patella

It is very uncertain whether percutaneous patellar osteosynthesis changes major adverse outcome: total events compared with open surgery (very low certainty).

1 finding from 1 review

Interventions for treating fractures of the patella in adults 2021 · Cochrane Headline outcomes only
RR 0.26 [0.14, 0.46]
3 studies · 145 participants
Very low

Percutaneous patellar osteosynthesis vs open surgery

Observer‐rated measures of knee function Knee function scores (see comment) · adults with fractures of the patella

It is very uncertain whether percutaneous patellar osteosynthesis changes observer‐rated measures of knee function Knee function scores (see… compared with open surgery (very low certainty).

1 finding from 1 review

Interventions for treating fractures of the patella in adults 2021 · Cochrane Headline outcomes only
SMD 1.01 [0.08, 1.95]
3 studies · 124 participants
Very low

Percutaneous patellar osteosynthesis vs open surgery

Health‐related quality of life · adults with fractures of the patella

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating fractures of the patella in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Percutaneous patellar osteosynthesis vs open surgery

Return to activity · adults with fractures of the patella

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating fractures of the patella in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Percutaneous patellar osteosynthesis vs open surgery

Cosmetic appearance · adults with fractures of the patella

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating fractures of the patella in adults 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Percutaneous insertion vs open surgery

Exit‐site/tunnel infection · chronic peritoneal dialysis patients

Percutaneous insertion showed no clear difference in exit‐site/tunnel infection compared with open surgery (moderate certainty).

1 finding from 1 review

Catheter type, placement and insertion techniques for preventing catheter‐related infections in chronic peritoneal… 2019 · Cochrane Headline outcomes only
RR 0.16 [0.02, 1.3]
2 studies · 96 participants
Moderate

Percutaneous insertion vs open surgery

Catheter removal or replacement · chronic peritoneal dialysis patients

It is very uncertain whether percutaneous insertion changes catheter removal or replacement compared with open surgery (very low certainty).

1 finding from 1 review

Catheter type, placement and insertion techniques for preventing catheter‐related infections in chronic peritoneal… 2019 · Cochrane Headline outcomes only
RR 0.24 [0.03, 2.04]
1 study · 61 participants
Very low

Laparoscopic vs open surgery

Infertilty at 12 months · females with inflammatory bowel disease

It is very uncertain whether laparoscopic changes infertilty at 12 months compared with open surgery (very low certainty).

1 finding from 1 review

The impact of surgical therapies for inflammatory bowel disease on female fertility 2019 · Cochrane Headline outcomes only
RR 0.7 [0.38, 1.27]
1 study · 19 participants
Very low

Laparoscopic vs open surgery

Infertility at 24 months · females with inflammatory bowel disease

The review found no eligible studies for this question.

1 finding from 1 review

The impact of surgical therapies for inflammatory bowel disease on female fertility 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laparoscopic vs open surgery

Miscarriage · females with inflammatory bowel disease

The review found no eligible studies for this question.

1 finding from 1 review

The impact of surgical therapies for inflammatory bowel disease on female fertility 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Laparoscopic vs open surgery

Stillbirth · females with inflammatory bowel disease

The review found no eligible studies for this question.

1 finding from 1 review

The impact of surgical therapies for inflammatory bowel disease on female fertility 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found