Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

412 questions · 464 findings · 104 reviews

No studies found 44 · 9.5%GRADE not reported 84 · 18.1%Very low 165 · 35.6%Low 113 · 24.4%Moderate 41 · 8.8%High 17 · 3.7%

INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) FOR PROMPTING/SUPPORT + STANDARD CARE vs usual care

Acceptability (of intervention): Leaving the studies early – any reason Loss to · patients with treatment compliance for people with serious mental illness

INFORMATION AND COMMUNICATION TECHNOLOGY (ICT) FOR PROMPTING/SUPPORT… showed no clear difference in acceptability (of intervention): Leaving the studies early – any… compared with STANDARD CARE (low certainty).

1 finding from 1 review

Early ventilation tubes vs watchful waiting

Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether early ventilation tubes changes hearing ‐ return to normal hearing Randomised by child compared with watchful waiting (treatment later if required) (very low certainty).

1 finding from 1 review

Early ventilation tubes vs watchful waiting

Presence/persistence of OME · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether early ventilation tubes changes presence/persistence of OME Randomised by child compared with watchful waiting (treatment later if required) (very low certainty).

1 finding from 1 review

Early ventilation tubes vs watchful waiting

Adverse event: persistent perforation · children aged 6 months to 12 years with otitis media with effusion (OME)

It is very uncertain whether early ventilation tubes changes adverse event: persistent perforation compared with watchful waiting (treatment later if required) (very low certainty).

1 finding from 1 review

Early shoulder mobilising exercises vs delayed shoulder mobilising exercises

Lymphoedema ‐ medium term · patients at risk for secondary upper limb lymphoedema after breast cancer treatment

It is very uncertain whether early shoulder mobilising exercises changes lymphoedema ‐ medium term compared with delayed shoulder mobilising exercises (very low certainty).

1 finding from 1 review

Intervention not reported

PTB (< 37w) ‐ PTB (<37w) ‐ Depth ≥15 to 17mm versus No Treatment · women with known obstetric outcomes

It is very uncertain whether the intervention changes PTB (< 37w) ‐ PTB (<37w) ‐ Depth ≥15 to 17mm versus No Treatment (very low certainty).

1 finding from 1 review