Dental caries · Children aged 5-7 years (early school-age)
In early school-age children (5-7 y) from a low-contamination area, one study reported higher DMFT/dmft in exposed than non-exposed children; the estimate was not pooled (ungraded).
1 finding from 1 review
Average enamel surface roughness · Extracted human teeth with early/artificial enamel lesions (in vitro)
In vitro, CPP-ACP markedly reduced enamel surface roughness versus control (SMD -8.21, 95% CI -10.37 to -6.04; ungraded).
1 finding from 1 review
Quantitative light-induced fluorescence (QLF), fluorescence loss · Patients (mainly children) with white spot lesions (WSL)
CPP-ACP toothpaste did not differ significantly from placebo paste (fluoride control) for white spot lesion remineralization on QLF (MD 0.08, 95% CI -0.91 to 1.08; ungraded).
1 finding from 1 review
Microbial reduction (viable count, log CFU/mL) · Patients with dental caries (in vivo cariogenic microorganisms, including children with early childhood caries)
In randomized clinical trials, photodynamic therapy significantly reduced cariogenic microbial counts versus untreated control (SMD -1.16, 95% CI -2.02 to -0.30; 2 trials), but heterogeneity was high (I2=70%) and considered too high to rely on; certainty was not graded.
1 finding from 1 review
Remineralisation of white spot lesions · Patients (mainly children) with white spot lesions (WSL)
One trial found professionally applied silicon tetrafluoride did not remineralise white spot lesions; ungraded.
1 finding from 1 review
Mean dmft (caries severity) · Children aged 0-5 years in North Africa
The pooled mean dmft was 2.95 (95% CI 1.86-4.67), with very high heterogeneity (I2=99.7%).
1 finding from 1 review
MEAN 2.95 [1.86, 4.67]
13 studies
GRADE not reported
Caries presence in primary teeth · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
It is very uncertain whether package of oral health education/promotion including oral hygiene… changes caries presence in primary teeth compared with standard care (very low certainty).
1 finding from 1 review
Dental caries · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
The review found no eligible studies for this question.
2 findings from 1 review
Mother microbiological presence (high-level mutans streptococci / lactobacilli) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
Oral health education/promotion (oral hygiene advice plus diet and… showed no clear difference in mother microbiological presence (high-level mutans streptococci /… compared with standard care; GRADE not reported.
1 finding from 1 review
Caries presence in primary teeth · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
It is very uncertain whether consumption of xylitol chewing gum by women (mothers) changes caries presence in primary teeth compared with consumption of CHX/xylitol gum by women, or CHX varnish applied to… (very low certainty).
1 finding from 1 review
Mother microbiological presence · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
1 finding from 1 review
Caries presence in top front four teeth · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
It is very uncertain whether package of oral health education/promotion including oral hygiene… changes caries presence in top front four teeth compared with standard care (very low certainty).
1 finding from 1 review
dmfs index score (decayed, missing, filled primary surfaces; range 0-80) · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
Advice about a healthy diet (including breastfeeding promotion and… showed no clear difference in dmfs index score (decayed, missing, filled primary surfaces; range… compared with standard care (low certainty).
1 finding from 1 review
Intervention not reported
Serum vitamin D (25(OH)D): ECC vs caries-free
The intervention led to lower serum vitamin D (25(OH)D): ECC vs caries-free; GRADE not reported.
1 finding from 1 review
Dental caries · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
Package of oral health education/promotion including oral hygiene… showed no clear difference in dmfs index score compared with standard care (low certainty).
2 findings from 1 review
Mother self-reported oral health behaviours · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
1 finding from 1 review
Intervention not reported
Pit-and-fissure caries progression (ICDAS), CO2 laser vs fluoride varnish alone
1 finding from 1 review
no estimate extracted
1 study
GRADE not reported
Child dental attendance · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
1 finding from 1 review
Plutzer 2008 reported dental attendance as cumulative child-visit categories (other data): intervention children more likely to have 1-2 visits, no difference for 3-4 visits, less likely for >=5 visits.
1 study
GRADE not reported
Caries presence in primary teeth · For interventions, pregnant women, mothers or other caregivers of infants in the first year of life; for outcomes, children up to 6 years…
Advice about a healthy diet (including breastfeeding promotion and… probably leads to lower caries presence in primary teeth compared with standard care (moderate certainty).
1 finding from 1 review
Child microbiological presence (any mutans streptococci colonisation) · For interventions, pregnant women and mothers of infants in the first year of life; for outcomes, children up to 6 years of age
Consumption of xylitol chewing gum by women (mothers) led to lower child microbiological presence (any mutans streptococci colonisation) compared with consumption of CHX/xylitol gum by women, or CHX varnish applied to…; GRADE not reported.
1 finding from 1 review
RR 0.60 [0.45, 0.81]
2 studies
GRADE not reported