Non-Cochrane · aetiology · PM30824766
A systematic review of the caries prevalence among children living in Chernobyl fallout countries.
Wolgin Michael, Filina Nicole, Shakavets Natalia, et al. · Scientific reports · 2019 · PubMed · doi:10.1038/s41598-019-39755-5
Full textEvery question was extracted from the full text, figures and supplements by two independent LLM extractors, disagreements adjudicated. Rows cite where in the review the value comes from.
Questions
30
current version
GRADE rated
0
No studies
0
Included studies
9
linked below
No studies 0 · 0%Ungraded 30 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Review question
| Element | Planned (methods) | Found (results) |
|---|---|---|
| Population | Ukrainian, Belarusian, and Russian children with primary, mixed, and permanent dentitions, born and permanently residing in areas with radioactive contamination | Children aged 5-7 y, 12-15 y, and mixed ages (mean ~12 y) from Ukraine, Belarus, and Russia (9 studies) |
| Intervention | Small-dose radiation exposure (residence in a radioactively contaminated area) | Residence in radioactively contaminated areas (weak ~1-5, low ~5-15, heavy ~15-40 Ci/km2) |
| Comparison | Absence of radiation exposure (non-exposed cohort); >=50 participants per group required | Residence in non-contaminated areas (<1 Ci/km2) |
| Outcomes | Rate of tooth decay (DMFT/dmft index: decayed, missing, and filled teeth); primary endpoint, no secondary endpoints | DMFT/dmft index (group mean +/- SD; per-study weighted mean difference exposed vs non-exposed). No pooling: heterogeneity I2 = 94% to 99.9% |
| Study designs | Observational studies with >=50 participants per group and a non-exposed comparison cohort | Cross-sectional studies (n=9) |
| Timing | Occurrence of tooth decay over time (PICOT 'Time'); not further specified | Cross-sectional (single examination); data collected 1987-2014 |
Search date: February 2017 to February 2018. Databases: PubMed; EMBASE/Ovid; Cochrane Central Register of Controlled Trials (CENTRAL); Cochrane Reviews; Scopus; eLIBRARY (Russian database); plus reference lists and national/international dissertation databases (hand-search)
Questions and results
Residence in weakly contaminated area (approx. 1-5 Ci/km2) vs Residence in non-contaminated (non-exposed) area (<1 Ci/km2)
Population: Children aged 5-7 years (early school-age)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience (DMFT/dmft index) weak contamination In early school-age children (5-7 y) from weakly contaminated areas, individual cross-sectional studies reported mostly higher but inconsistent DMFT/dmft in exposed vs non-exposed children; the review did not pool the data and drew no firm conclusion (ungraded). Source: Figure 2a; Petruniv 2012 · same question in other reviews | WMD 0.45 [0.32, 0.58] | 1 study · 117 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In early school-age children (5-7 y) from weakly contaminated areas, individual cross-sectional studies reported mostly higher but inconsistent DMFT/dmft in exposed vs non-exposed children; the review did not pool the data and drew no firm conclusion (ungraded). Source: Figure 2a; Shapovalova 2001 · same question in other reviews | WMD 6.51 [6.11, 6.91] | 1 study · 27 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In early school-age children (5-7 y) from weakly contaminated areas, individual cross-sectional studies reported mostly higher but inconsistent DMFT/dmft in exposed vs non-exposed children; the review did not pool the data and drew no firm conclusion (ungraded). Source: Figure 2a; Shapovalova 2001 · same question in other reviews | WMD 4.65 [4.50, 4.80] | 1 study · 165 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In early school-age children (5-7 y) from weakly contaminated areas, individual cross-sectional studies reported mostly higher but inconsistent DMFT/dmft in exposed vs non-exposed children; the review did not pool the data and drew no firm conclusion (ungraded). Source: Figure 2a; Petruniv 2012 · same question in other reviews | WMD 0.22 [0.10, 0.34] | 1 study · 117 participants | Ungraded |
Residence in low-contamination area (approx. 5-15 Ci/km2) vs Residence in non-contaminated (non-exposed) area (<1 Ci/km2)
Population: Children aged 5-7 years (early school-age)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience (DMFT/dmft index) low contamination In early school-age children (5-7 y) from a low-contamination area, one study reported higher DMFT/dmft in exposed than non-exposed children; the estimate was not pooled (ungraded). Source: Figure 2a; Shapovalova 2001 · same question in other reviews | WMD 5.22 [4.72, 5.72] | 1 study · 36 participants | Ungraded |
Residence in heavily contaminated area (approx. 15-40 Ci/km2) vs Residence in non-contaminated (non-exposed) area (<1 Ci/km2)
Population: Children aged 5-7 years (early school-age)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience (DMFT/dmft index) heavy contamination In early school-age children (5-7 y) from heavily contaminated areas, individual studies gave conflicting DMFT/dmft differences (some favouring exposed, some non-exposed); the review did not pool them (ungraded). Source: Figure 2a; Melnichenko 1997 · same question in other reviews | WMD -0.81 [-1.06, -0.56] | 1 study · 80 participants | Ungraded |
Dental caries experience (DMFT/dmft index) heavy contamination In early school-age children (5-7 y) from heavily contaminated areas, individual studies gave conflicting DMFT/dmft differences (some favouring exposed, some non-exposed); the review did not pool them (ungraded). Source: Figure 2a; Melnichenko 1997 · same question in other reviews | WMD -1.03 [-1.36, -0.70] | 1 study · 78 participants | Ungraded |
Dental caries experience (DMFT/dmft index) heavy contamination In early school-age children (5-7 y) from heavily contaminated areas, individual studies gave conflicting DMFT/dmft differences (some favouring exposed, some non-exposed); the review did not pool them (ungraded). Source: Figure 2a; Smolyar 1995 · same question in other reviews | WMD 1.75 [1.73, 1.77] | 1 study · 1474 participants | Ungraded |
Dental caries experience (DMFT/dmft index) heavy contamination In early school-age children (5-7 y) from heavily contaminated areas, individual studies gave conflicting DMFT/dmft differences (some favouring exposed, some non-exposed); the review did not pool them (ungraded). Source: Figure 2a; Melnichenko 1997 · same question in other reviews | WMD 1.05 [0.84, 1.26] | 1 study · 80 participants | Ungraded |
Residence in weakly contaminated area (approx. 1-5 Ci/km2) vs Residence in non-contaminated (non-exposed) area (<1 Ci/km2)
Population: Children aged 12-15 years (adolescents)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience (DMFT/dmft index) weak contamination In adolescents (12-15 y) from weakly contaminated areas, individual studies mostly reported higher DMFT/dmft in exposed children but with wide variation; the review did not pool the data (ungraded). Source: Figure 2b; Petruniv 2012 · same question in other reviews | WMD 1.88 [1.66, 2.10] | 1 study · 143 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In adolescents (12-15 y) from weakly contaminated areas, individual studies mostly reported higher DMFT/dmft in exposed children but with wide variation; the review did not pool the data (ungraded). Source: Figure 2b; Shapovalova 2001 · same question in other reviews | WMD 3.49 [3.26, 3.72] | 1 study · 30 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In adolescents (12-15 y) from weakly contaminated areas, individual studies mostly reported higher DMFT/dmft in exposed children but with wide variation; the review did not pool the data (ungraded). Source: Figure 2b; Petruniv 2012 · same question in other reviews | WMD 2.13 [1.94, 2.32] | 1 study · 151 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In adolescents (12-15 y) from weakly contaminated areas, individual studies mostly reported higher DMFT/dmft in exposed children but with wide variation; the review did not pool the data (ungraded). Source: Figure 2b; Petruniv 2012 · same question in other reviews | WMD 2.27 [2.06, 2.48] | 1 study · 129 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In adolescents (12-15 y) from weakly contaminated areas, individual studies mostly reported higher DMFT/dmft in exposed children but with wide variation; the review did not pool the data (ungraded). Source: Figure 2b; Kushner 1999 · same question in other reviews | WMD 0.02 [-0.11, 0.15] | 1 study · 137 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In adolescents (12-15 y) from weakly contaminated areas, individual studies mostly reported higher DMFT/dmft in exposed children but with wide variation; the review did not pool the data (ungraded). Source: Figure 2b; Kushner 1999 · same question in other reviews | WMD -0.18 [-0.35, -0.01] | 1 study · 135 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In adolescents (12-15 y) from weakly contaminated areas, individual studies mostly reported higher DMFT/dmft in exposed children but with wide variation; the review did not pool the data (ungraded). Source: Figure 2b; Petruniv 2012 · same question in other reviews | WMD 0.33 [0.11, 0.55] | 1 study · 127 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In adolescents (12-15 y) from weakly contaminated areas, individual studies mostly reported higher DMFT/dmft in exposed children but with wide variation; the review did not pool the data (ungraded). Source: Figure 2b; Shapovalova 2001 · same question in other reviews | WMD 2.02 [1.95, 2.09] | 1 study · 161 participants | Ungraded |
Dental caries experience (DMFT/dmft index) weak contamination In adolescents (12-15 y) from weakly contaminated areas, individual studies mostly reported higher DMFT/dmft in exposed children but with wide variation; the review did not pool the data (ungraded). Source: Figure 2b; Spivak 2004 · same question in other reviews | WMD 3.40 [2.71, 4.09] | 1 study · 219 participants | Ungraded |
Residence in low-contamination area (approx. 5-15 Ci/km2) vs Residence in non-contaminated (non-exposed) area (<1 Ci/km2)
Population: Children aged 12-15 years (adolescents)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience (DMFT/dmft index) low contamination In adolescents (12-15 y) from a low-contamination area, individual studies reported higher DMFT/dmft in exposed than non-exposed children; not pooled (ungraded). Source: Figure 2b; Shapovalova 2001 · same question in other reviews | WMD 4.16 [3.84, 4.48] | 1 study · 58 participants | Ungraded |
Dental caries experience (DMFT/dmft index) low contamination In adolescents (12-15 y) from a low-contamination area, individual studies reported higher DMFT/dmft in exposed than non-exposed children; not pooled (ungraded). Source: Figure 2b; Shapovalova 2001 · same question in other reviews | WMD 3.48 [3.42, 3.54] | 1 study · 38 participants | Ungraded |
Residence in heavily contaminated area (approx. 15-40 Ci/km2) vs Residence in non-contaminated (non-exposed) area (<1 Ci/km2)
Population: Children aged 12-15 years (adolescents)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience (DMFT/dmft index) heavy contamination In adolescents (12-15 y) from heavily contaminated areas, individual studies gave inconsistent DMFT/dmft differences; the review did not pool them and drew no firm conclusion (ungraded). Source: Figure 2b; Melnichenko 1997 · same question in other reviews | WMD 0.67 [0.50, 0.84] | 1 study · 79 participants | Ungraded |
Dental caries experience (DMFT/dmft index) heavy contamination In adolescents (12-15 y) from heavily contaminated areas, individual studies gave inconsistent DMFT/dmft differences; the review did not pool them and drew no firm conclusion (ungraded). Source: Figure 2b; Sevbitov 2006 · same question in other reviews | WMD 4.45 [3.99, 4.91] | 1 study · 265 participants | Ungraded |
Dental caries experience (DMFT/dmft index) heavy contamination In adolescents (12-15 y) from heavily contaminated areas, individual studies gave inconsistent DMFT/dmft differences; the review did not pool them and drew no firm conclusion (ungraded). Source: Figure 2b; Kushner 1999 · same question in other reviews | WMD 1.06 [0.92, 1.20] | 1 study · 143 participants | Ungraded |
Dental caries experience (DMFT/dmft index) heavy contamination In adolescents (12-15 y) from heavily contaminated areas, individual studies gave inconsistent DMFT/dmft differences; the review did not pool them and drew no firm conclusion (ungraded). Source: Figure 2b; Melnichenko 1997 · same question in other reviews | WMD -0.04 [-0.31, 0.23] | 1 study · 73 participants | Ungraded |
Residence in weakly contaminated area (approx. 1-5 Ci/km2) vs Residence in non-contaminated (non-exposed) area (<1 Ci/km2)
Population: Children of mixed ages (mean approximately 12 years; no age separation)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience (DMFT/dmft index) weak contamination In children of mixed ages from a weakly contaminated area, one study reported higher DMFT/dmft in exposed than non-exposed children; not pooled (ungraded). Source: Figure 2c; Petruniv 2012 · same question in other reviews | WMD 1.40 [1.34, 1.46] | 1 study · 1302 participants | Ungraded |
Residence in heavily contaminated area (approx. 15-40 Ci/km2) vs Residence in non-contaminated (non-exposed) area (<1 Ci/km2)
Population: Children of mixed ages (mean approximately 12 years; no age separation)
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Dental caries experience (DMFT/dmft index) heavy contamination In children of mixed ages from heavily contaminated areas, individual studies reported modestly higher DMFT/dmft in exposed children; the review did not pool them and drew no firm conclusion (ungraded). Source: Figure 2c; Melnichenko 1994 · same question in other reviews | WMD 0.54 [0.43, 0.65] | 1 study · 102 participants | Ungraded |
Dental caries experience (DMFT/dmft index) heavy contamination In children of mixed ages from heavily contaminated areas, individual studies reported modestly higher DMFT/dmft in exposed children; the review did not pool them and drew no firm conclusion (ungraded). Source: Figure 2c; Sevbitov 2014 · same question in other reviews | WMD 1.92 [1.87, 1.97] | 1 study · 600 participants | Ungraded |
Dental caries experience (DMFT/dmft index) heavy contamination In children of mixed ages from heavily contaminated areas, individual studies reported modestly higher DMFT/dmft in exposed children; the review did not pool them and drew no firm conclusion (ungraded). Source: Figure 2c; Melnichenko 1997 · same question in other reviews | WMD 0.65 [0.64, 0.66] | 1 study · 1033 participants | Ungraded |
Dental caries experience (DMFT/dmft index) heavy contamination In children of mixed ages from heavily contaminated areas, individual studies reported modestly higher DMFT/dmft in exposed children; the review did not pool them and drew no firm conclusion (ungraded). Source: Figure 2c; Melnichenko 1994 · same question in other reviews | WMD 1.47 [1.37, 1.57] | 1 study · 395 participants | Ungraded |
Dental caries experience (DMFT/dmft index) heavy contamination In children of mixed ages from heavily contaminated areas, individual studies reported modestly higher DMFT/dmft in exposed children; the review did not pool them and drew no firm conclusion (ungraded). Source: Figure 2c; Melnichenko 1994 · same question in other reviews | WMD 0.90 [0.80, 1.00] | 1 study · 365 participants | Ungraded |
Included primary studies 9
Open as a trial list| Study | Also included by | Outcomes it informs here | Trial PICO | Results |
|---|---|---|---|---|
| Kushner 1999 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Melnichenko 1994 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Melnichenko 1997 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Petruniv 2012 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Sevbitov 2006 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Sevbitov 2014 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Shapovalova 2001 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Smolyar 1995 matched by author and year (probable) | this review only | not stated | not extracted yet | not extracted yet |
| Spivak 2004 Caries prevalence, oral health behavior, and attitudes in children residing in radiation‐contaminated and ‐noncontaminated towns in Ukraine DOI:10.1111/j.1600-0528.2004.00003.x | this review only | not stated | not extracted yet | not extracted yet |