Maternal mortality ‐ not reported · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in maternal mortality (all causes) compared with placebo or standard care alone (moderate certainty).
1 finding from 1 review
Serious maternal morbidity · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in serious maternal morbidity (any) compared with placebo or standard care alone (high certainty).
1 finding from 1 review
Maternal blood loss of 500 mL or greater · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid may leads to lower blood loss 500 mL or more after randomisation compared with placebo or standard care alone (low certainty).
1 finding from 1 review
Blood transfusion · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in blood transfusion (any) compared with placebo or standard care alone (moderate certainty).
1 finding from 1 review
Hysterectomy to control bleeding · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in surgical intervention to control bleeding: Hysterectomy compared with placebo or standard care alone (high certainty).
1 finding from 1 review
Side effects of the intervention: Any maternal vascular occlusive event · women with primary postpartum haemorrhage following vaginal or caesarean birth
Standard care plus IV tranexamic acid showed no clear difference in side effects of the intervention: Any maternal vascular occlusive… compared with placebo or standard care alone (moderate certainty).
1 finding from 1 review
Pain (short term) WOMAC scale from 0 to 20 points (higher is worse pain). · patients with hip osteoarthritis
1 finding from 1 review
Function (short‐term) DRI scale from: 0 to 100 (higher is worse function). · patients with hip osteoarthritis
1 finding from 1 review
Quality of life (short‐term) GSI scale from 0 to 10 (higher is worse quality of life). · patients with hip osteoarthritis
1 finding from 1 review
Number of participants reporting an adverse event · patients with hip osteoarthritis
The review found no eligible studies for this question.
1 finding from 1 review
Withdrawals due to adverse events · patients with hip osteoarthritis
The review found no eligible studies for this question.
1 finding from 1 review
Serious adverse events · patients with hip osteoarthritis
The review found no eligible studies for this question.
1 finding from 1 review
Cardiovascular mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin showed no clear difference in cardiovascular mortality compared with aspirin alone (moderate certainty).
1 finding from 1 review
All‐cause mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin showed no clear difference in all‐cause mortality compared with aspirin alone (low certainty).
1 finding from 1 review
Fatal or nonfatal myocardial infarction · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin probably leads to lower fatal and non‐fatal myocardial infarction compared with aspirin alone (moderate certainty).
1 finding from 1 review
Fatal and non‐fatal ischaemic stroke · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin probably leads to lower fatal and non‐fatal ischaemic stroke compared with aspirin alone (moderate certainty).
1 finding from 1 review
Adverse events · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
1 finding from 1 review
Major bleeding · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin probably leads to higher major bleeding compared with aspirin alone (moderate certainty).
1 finding from 1 review
Minor bleeding · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease
clopidogrel plus aspirin probably leads to higher minor bleeding compared with aspirin alone (moderate certainty).
1 finding from 1 review
All‐cause mortality · patients with heart failure
Does treatment guided by serial BNP or NT‐proBNP monitoring improve… showed no clear difference in all‐cause mortality compared with treatment guided by clinical assessment alone? (low certainty).
1 finding from 1 review