What do systematic reviews say?

GM-CSF vs Antimycotic mouthrinse

Granulocyte macrophage-colony stimulating factor (GM-CSF) led to lower time to heal mucositis (days) compared with antimycotic mouthrinse; GRADE not reported.

• Interventions for treating oral mucositis for patients with cancer receiving treatment 2010 · Cochrane All outcomes
  MD -2.40 [-4.15, -0.65]
  1 study · 40 participants
  GRADE not reported

GM-CSF vs povidone‐iodine

Granulocyte macrophage-colony stimulating factor (GM-CSF) led to lower time to heal mucositis (days) compared with povidone iodine; GRADE not reported.

• Interventions for treating oral mucositis for patients with cancer receiving treatment 2010 · Cochrane All outcomes
  MD -3.50 [-4.14, -2.86]
  1 study · 31 participants
  GRADE not reported

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash vs Sucralfate mouthwash

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash showed no clear difference in interruptions to cancer treatment compared with sucralfate mouthwash; GRADE not reported.

• Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors 2017 · Cochrane All outcomes

  RT to head and neck
  RR 0.13 [0.01, 2.36]
  1 study · 40 participants
  GRADE not reported

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash vs Sucralfate mouthwash

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash showed no clear difference in normalcy of diet (percutaneous endoscopic gastrostomy) compared with sucralfate mouthwash; GRADE not reported.

• Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors 2017 · Cochrane All outcomes

  RT to head and neck
  RR 0.18 [0.01, 3.56]
  1 study · 40 participants
  GRADE not reported

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash vs Sucralfate mouthwash

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash showed no clear difference in oral mucositis (severe) compared with sucralfate mouthwash; GRADE not reported.

• Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors 2017 · Cochrane All outcomes

  RT to head and neck
  RR 0.54 [0.24, 1.21]
  1 study · 40 participants
  GRADE not reported

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash vs Sucralfate mouthwash

Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash showed no clear difference in oral mucositis (moderate to severe) compared with sucralfate mouthwash; GRADE not reported.

• Interventions for preventing oral mucositis in patients with cancer receiving treatment: cytokines and growth factors 2017 · Cochrane All outcomes

  RT to head and neck
  RR 0.96 [0.80, 1.14]
  1 study · 40 participants
  GRADE not reported

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

Micronutrient or macronutrient supplementation interventions in… showed no clear difference in height‐for‐age (z‐score) compared with no intervention, or placebo to reduce stunting (height‐for‐age,… (low certainty).

• Nutritional interventions for preventing stunting in children (birth to 59 months) living in urban slums in low‐ and… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 2601 participants
  Low

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

• Nutritional interventions for preventing stunting in children (birth to 59 months) living in urban slums in low‐ and… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 653 participants
  Low

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

• Nutritional interventions for preventing stunting in children (birth to 59 months) living in urban slums in low‐ and… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 324 participants
  Moderate

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

• Nutritional interventions for preventing stunting in children (birth to 59 months) living in urban slums in low‐ and… 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 315 participants
  Low

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

It is very uncertain whether micronutrient or macronutrient supplementation interventions in… changes length velocity (cm/month) compared with no intervention, or placebo to reduce stunting (height‐for‐age,… (very low certainty).

• Nutritional interventions for preventing stunting in children (birth to 59 months) living in urban slums in low‐ and… 2019 · Cochrane Headline outcomes only
  MD 0.22 [0.02, 0.43]
  1 study · 75 participants
  Very low

Micronutrient or macronutrient supplementation interventions in children vs no intervention, or placebo to reduce stunting (height‐for‐age, length velocity, and length at 12 months)

Micronutrient or macronutrient supplementation interventions in… showed no clear difference in length (cm) at 12 months compared with no intervention, or placebo to reduce stunting (height‐for‐age,… (low certainty).

• Nutritional interventions for preventing stunting in children (birth to 59 months) living in urban slums in low‐ and… 2019 · Cochrane Headline outcomes only
  MD 2.3
  1 study · 100 participants
  Low

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

• Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 74 participants
  Very low
• Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 74 participants
  Very low
• Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
  OR 1.26 [0.4, 3.93]
  1 study · 51 participants
  Low

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

• Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 121 participants
  GRADE not reported

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

The review found no eligible studies for this question.

• Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

The review found no eligible studies for this question.

• Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ LUNA (laparoscopic uterosacral ligament nerve ablation) vs diagnostic laparoscopy/other treatments

• Surgical interventions for the management of chronic pelvic pain in women 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 74 participants
  GRADE not reported

Different etching materials (phosphoric acid, polyacrylic acid, maleic acid, etc.), acid concentrations or etching times vs An alternative etching material, concentration or etching time

The review found no eligible studies for this question.

• Enamel etching for bonding fixed orthodontic braces 2013 · Cochrane All outcomes
  We identified no eligible trial that examined the effects of conventional etchants with respect to different etching concentrations or etching times for the bonding of fixed orthodontic appliances. No eligible RCTs…
  Studies not reported
  No studies found

Any topical or systemic intervention (topical/systemic steroids, ciclosporin, tacrolimus, retinoids, anti-malarials, biologics, phototherapy, surgery) vs Placebo, no treatment, another active intervention, or a different dose of the same intervention

The review found no eligible studies for this question.

• Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes
  No studies reported this outcome.
  0 studies
  No studies found

Any topical or systemic intervention (topical/systemic steroids, ciclosporin, tacrolimus, retinoids, anti-malarials, biologics, phototherapy, surgery) vs Placebo, no treatment, another active intervention, or a different dose of the same intervention

The review found no eligible studies for this question.

• Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes
  None of the included studies assessed the effectiveness of treatments of genital ELP; thus, this outcome was not reported.
  0 studies
  No studies found